Results 71 to 80 of about 2,699,909 (326)

Co-creative expertise: Auran games and fury: A case study [PDF]

open access: yes, 2009
This article discusses the ways in which the relations among professional and non-professional participants in co-creative relations are being reconfigured as part of the shift from a closed industrial paradigm of expertise toward open and distributed ...
Banks, John
core   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Stepped-wedge cluster randomised trial of a smoking cessation counselling training programme for midwives treating women with functional health illiteracy and low socioeconomic status (PROMISE): a study protocol

open access: yesTrials, 2020
Background In the Netherlands, midwives are required to use the ‘V-MIS’ (Minimal Intervention Strategy for Midwives) smoking cessation counselling protocol to help pregnant women quit smoking.
Jeroen Bommelé   +5 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Current State of the Vaccine Prophylaxis of Particularly Dangerous Infections

open access: yesПроблемы особо опасных инфекций, 2016
Considered are the problems of handling of the vaccine strains Yersinia pestis EV NIIEG, Bacillus anthracis STI-1, Francisella tularensis 15 NIIEG, and Brucella abortus 19 BA, utilized for manufacturing of live vaccines against particularly dangerous ...
L. V. Sayapina   +2 more
doaj   +1 more source

Explicit recognition of emotional facial expressions is shaped by expertise: evidence from professional actors [PDF]

open access: yes, 2013
Can reading others' emotional states be shaped by expertise? We assessed processing of emotional facial expressions in professional actors trained either to voluntary activate mimicry to reproduce character's emotions (as foreseen by the “Mimic Method”),
Conson, Massimiliano   +6 more
core   +2 more sources

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Association of child abuse and neglect training with filing reports of concern to child welfare services: a cross-sectional study

open access: yesBMC Oral Health
Background The aptitude, knowledge, and competence of dental health personnel on child abuse and neglect (CAN) is not optimal for deciding when to file a report of concern to child welfare services (CWS). Objectives The aim of this study was, firstly, to
Nancy Birungi   +3 more
doaj   +1 more source

Dialogue expertise in man-machine systems [PDF]

open access: yes, 1989
The present paper considers the nature of interaction in man-machine systems with special attention to the role of dialogue. Based upon this understanding, a concept of 'dialogue expertise' is derived in a specific facility for mediation.
Weir, G.R.S.
core  

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