Results 71 to 80 of about 4,635,657 (309)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Medically-oriented design for explainable AI for stress prediction from physiological measurements
BMC Medical Informatics and Decision Making, 2022 Background In the last decade, a lot of attention has been given to develop artificial intelligence (AI) solutions for mental health using machine learning.
Dalia Jaber +3 more
doaj +1 more source
Implications of causality in artificial intelligence
Frontiers in Artificial IntelligenceOver the last decade, investment in artificial intelligence (AI) has grown significantly, driven by technology companies and the demand for PhDs in AI. However, new challenges have emerged, such as the ‘black box’ and bias in AI models.
Luís Cavique
doaj +1 more source
Explaining Machines: Social Management of Incomprehensible Algorithms. Introduction
Sociologica, 2023 This short introduction presents the symposium ‘Explaining Machines’. It locates the debate about Explainable AI in the history of the reflection about AI and outlines the issues discussed in the contributions.
Elena Esposito
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
The effectiveness of explainable AI on human factors in trust models
Scientific ReportsExplainable AI has garnered significant traction in science communication research. Prior empirical studies have firmly established that explainable AI communication could improve trust in AI and that trust in AI engineers was argued to be an under ...
Justin C. Cheung, Shirley S. Ho
doaj +1 more source
International Review of Research in Open and Distributed LearningThis study examined an online professional development program integrating artificial intelligence (AI) literacy into mathematics instruction through unplugged, explainable machine-learning activities.
Woonhee Sung, Yasemin Gunpinar
doaj +1 more source
Explainable AI for Safe and Trustworthy Autonomous Driving: A Systematic Review [PDF]
IEEE transactions on intelligent transportation systems (Print)Artificial Intelligence (AI) shows promising applications for the perception and planning tasks in autonomous driving (AD) due to its superior performance compared to conventional methods.
Anton Kuznietsov +4 more
semanticscholar +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source