Results 71 to 80 of about 1,214,867 (285)

A Scoresheet for Explainable AI

open access: yesInternational Joint Conference on Autonomous Agents and Multiagent Systems
Explainability is important for the transparency of autonomous and intelligent systems and for helping to support the development of appropriate levels of trust. There has been considerable work on developing approaches for explaining systems and there are standards that specify requirements for transparency.
Winikoff, Michael   +2 more
openaire   +3 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Informing Design and Research Concerning Conversationally Explainable AI Systems by Collecting and Distilling Human Explanatory Dialogues

open access: yesInformation
Research into conversationally explainable artificial intelligence (CXAI) aims to emulate the interactive and co-constructive nature of explanations. From the perspective of human-centredness, previous work has shown that AI users prefer conversational ...
Alexander Berman, Christine Howes
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

A Philosophical Approach for a Human-centered Explainable AI [PDF]

open access: yes, 2020
Requests for technical specifications on the notion of explainability of AI are urgent, although the definitions proposed are sometimes confusing. It is clear from the available literature that it is not easy to provide explicit, discrete and general ...
Bertolaso M, Capone L
core  

Explainable Artificial Intelligence Models for Predicting Depression Based on Polysomnographic Phenotypes

open access: yesBioengineering
Depression is a common mental health disorder and a leading contributor to mortality and morbidity. Despite several advancements, the current screening methods have limitations in enabling the robust and automated detection of depression, thereby ...
Doljinsuren Enkhbayar   +6 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Use of explainable AI on slit-lamp images of anterior surface of eyes to diagnose allergic conjunctival diseases

open access: yesAllergology International
Background: Artificial intelligence (AI) is a promising new technology that has the potential of diagnosing allergic conjunctival diseases (ACDs). However, its development is slowed by the absence of a tailored image database and explainable AI models ...
Michiko Yonehara   +22 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

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