Results 91 to 100 of about 5,977,377 (233)

RAFE-XAI: A Retrieval-Augmented Feature Engineering and Explainable NLP Framework for Urban Infrastructure Risk Classification

Mathematics
Urban infrastructure systems increasingly depend on textual reports generated by citizens, inspection teams, maintenance units, emergency platforms, and smart city services.
Abdulaziz Almaleh, Abdullah M. Alqahtani
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Implementation of STEP Application Protocol 224 in an automated manufacturing planning system.

, 2002
This paper reports the results of an on-going research project at Cranfield University in collaboration with a leading consultant company. A major objective of the research to develop a new generation process planning system using the latest tools and ...
J X Gao, R Sharma, Sharma, R., Gao, James X.   +3 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Explainable image recognition with graph-based feature extraction

Deep learning models have proven remarkably adept at extracting salient features from raw data, driving state-of-the-art performance across many domains.
Kuttichira, Deepthi P., Wang, Lipo, Azam, Basim, Verma, Brijesh, Kuttichira, Deepthi P, Rahman, Ashfaqur   +5 more
core   +1 more source

Engineering-Oriented Explainable Machine Learning and Digital Twin Framework for Sustainable Dairy Production and Environmental Impact Optimisation

Algorithms
Enhancing productivity while reducing environmental impact presents a major engineering challenge in sustainable dairy farming. This study proposes an engineering-oriented explainable machine learning and digital twin framework for multi-objective ...
Ruiming Xing, Baihua Li, Shirin Dora, Michael Whittaker, Janette Mathie   +4 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Novel accurate classification system developed using order transition pattern feature engineering technique with physiological signals

Scientific Reports
This paper presents a novel, explainable feature engineering framework for classifying EEG and ECG signals with high accuracy. The proposed method employs the Order Transition Pattern (OTPat) feature extractor.
Mehmet Ali Gelen, Prabal Datta Barua, Irem Tasci, Gulay Tasci, Emrah Aydemir, Sengul Dogan, Turker Tuncer, U. R. Acharya   +7 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Retrenching partial requirements into system definitions: A simple feature interaction case study

, 2003
In conventional model-oriented formal refinement, the abstract model is supposed to capture all the properties of interest in the system, in an as-clutter-free-as-possible manner. Subsequently, the refinement process guides development inexorably towards
Poppleton, Michael, Banach, Richard
core   +2 more sources