Results 41 to 50 of about 66,453 (258)

CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression

open access: yesAdvanced Science, EarlyView.
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao   +27 more
wiley   +1 more source

Macrophage‐derived MLKL in alcohol‐associated liver disease: Regulation of phagocytosis

open access: yesHepatology, EarlyView., 2022
EtOH causes leaky gut allowing bacteria and PAMPs into the liver, resulting in hepatic inflammation and injury. We demonstrate that LPS induces STAT1‐mediated expression and phosphorylation of MLKL in macrophages and identify a novel function that myeloid MLKL translocates to phagosomes and lysosomes and regulates phagocytosis, which contributes to the
Xiaoqin Wu   +16 more
wiley   +1 more source

Callogenesis, growth and bioactive compounds of kaffir lime (Citrus hystrix DC.) callus derived from leaf and stem explants [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST)
Differences in plant organs that are used as sources of explants can cause differences in callus growth and synthesized bioactive compounds. The objective of this study was to induce calli from different sources of explants and analyze their growth and
Reva Suzana   +2 more
doaj  

Multiplicação in vitro e alongamento das brotações micropropagadas do porta-enxerto 'Tsukuba 1'(Prunus persica L.) In vitro multiplication and elongation of the micropropagation shoots of the roostock of 'Tsukuba 1' (Prunus persica L.)

open access: yesRevista Brasileira de Fruticultura, 2009
Objetivou-se avaliar o efeito da fonte e concentração de citocinina e da composição dos sais presentes no meio de cultivo, na multiplicação in vitro do porta-enxerto 'Tsukuba 1' (Prunus persica L.).
Elizete Beatriz Radmann   +3 more
doaj   +1 more source

Recent Advances in Laser‐Induced Graphene‐Based Gas Sensors: From Sensing Mechanisms to Biomedical Applications

open access: yesAdvanced Science, EarlyView.
Laser‐induced graphene (LIG) provides a scalable, laser‐direct‐written route to porous graphene architecture with tunable chemistry and defect density. Through heterojunction engineering, catalytic functionalization, and intrinsic self‐heating, LIG achieves highly sensitive and selective detection of NOX, NH3, H2, and humidity, supporting next ...
Md Abu Sayeed Biswas   +6 more
wiley   +1 more source

The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression

open access: yesHepatology, EarlyView., 2022
Loss of NOX4 in HCC tumor cells induces metabolic reprogramming in a Nrf2/MYC‐dependent manner to promote HCC progression. Abstract Background and Aims The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in ...
Irene Peñuelas‐Haro   +14 more
wiley   +1 more source

Clonal micropropagation of peppermint (Mentha piperita L.) varieties of Ukrainian breeding

open access: yesPlant Varieties Studying and Protection, 2016
Purpose. Developing technology for clonal micropropagation of peppermint (Mentha piperita L.) plants of Ukrainian breeding based on the complex of methods of isolated tissue and organ culture in vitro. Methods.
Т. Є. Таланкова-Середа   +2 more
doaj   +1 more source

Effect of the Carbon Source and Plant Growth Regulators (PGRs) in the Induction and Maintenance of an In Vitro Callus Culture of Taraxacum officinale (L) Weber Ex F.H. Wigg

open access: yesAgronomy, 2021
Taraxacum officinale (L.) Weber ex F.H. Wigg, commonly known as dandelion, is a cosmopolitan and perennial weed, which has medicinal properties.
María Eugenia Martinez   +4 more
doaj   +1 more source

Single explant tumor of H358 enriches ‘mutation-free’ subpopulation.

open access: yes, 2013
(A) One out of four H358 explant tumor generated show presence of TP53 in the genome, indicating enrichment of the elusive ‘mutation-free’ subpopulation.
Chiou Mee Kong (281921)   +4 more
core   +1 more source

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang   +8 more
wiley   +1 more source

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