Animal Research and One Health, EarlyView.The experimental framework of the study encompasses sample collection, single‐cell data analysis, and experimental validation. Abstract Understanding differences in chromatin state and changes in gene regulatory landscape of placode (Pc) and dermal condensate are crucial for decoding hair follicle (HF) morphogenesis programs.
Fang Li +5 more
wiley +1 more source
Explant culture of adult goldfish retina: A model for the study of CNS regeneration [PDF]
, 1979 Gary E. Landreth, Bernard W. Agranoff
openalex +1 more source
Response and Resistance to Paradox-Breaking BRAF Inhibitor in Melanomas [PDF]
, 2018 FDA-approved BRAF inhibitors produce high response rates and improve overall survival in patients with BRAF V600E/K-mutant melanoma, but are linked to pathologies associated with paradoxical ERK1/2 activation in wild-type BRAF cells.
Aplin, Andrew E. +10 more
core +1 more source
Amyloid-β slows cilia movement along the ventricle, impairs fluid flow, and exacerbates its neurotoxicity in explant culture. [PDF]
Sci Rep, 2023 Makibatake R, Oda S, Yagi Y, Tatsumi H.
europepmc +1 more source
Assessment of the Integrity and Function of Human Term Placental Explants in Short-Term Culture
Methods and ProtocolsHuman placental explants (HPEs) culture has generated significant interest as a valuable in vitro model for studying tissue functions in response to adverse conditions, such as fluctuations in oxygen levels, nutrient availability, exposure to pathogenic ...
Carolina López-Guzmán +3 more
doaj +1 more source
Loss of TRIM21 drives UVB‐induced systemic inflammation by regulating DNA‐sensing pathways
Arthritis &Rheumatology, Accepted Article.Background Patients with systemic lupus erythematosus (SLE) experience photosensitivity, with exposure to ultraviolet light B (UVB) driving lupus flares and triggering symptoms like joint pain, fatigue, and cutaneous lesions. Although the mechanism(s) linking UVB exposure to systemic effects are unclear, type I interferons (IFNs) are known to play a ...
Gantsetseg Tumurkhuu +17 more
wiley +1 more source
Explant culture of adult goldfish retina: effect of prior optic nerve crush [PDF]
, 1976 Gary E. Landreth, Bernard W. Agranoff
openalex +1 more source
In vitro myelination using explant culture of dorsal root ganglia: An efficient tool for analyzing peripheral nerve differentiation and disease modeling. [PDF]
PLoS One, 2023 Numata-Uematasu Y +5 more
europepmc +1 more source
IN VITRO PROPAGATION OF DENDROBIUM AND PHALAENOPSIS THROUGH TISSUE CULTURE FOR CONSERVATION
AGRIVITA Journal of Agricultural Science, 2012 The studies were focused on developing an efficient and effective propagation protocol for orchid species from genera Dendrobioum and Phalaenopsis through tissue culture.
Lita Soetopo, Sri Lestari Purnamaningsih
doaj
Pharmacokinetics of betamethasone in pre‐eclampsia: An in vivo and ex vivo study
British Journal of Clinical Pharmacology, EarlyView.Aims To enhance understanding of betamethasone and its metabolites' pharmacokinetics in pregnancy, specifically early‐onset pre‐eclampsia, through a population pharmacokinetic model. Additionally, to investigate the placental metabolism and transfer of betamethasone and its main metabolites.
Sam Schoenmakers +15 more
wiley +1 more source