Results 131 to 140 of about 3,692,560 (357)

Data on the cost effective surface sterilization method for C.carandas (L.) seeds and callus induction from aseptic seedling

Data in Brief, 2016
Surface sterilization of explant is an important and most sensitive step in plant tissue culture. Inappropriate concentrations of sterilants have lethal effect in cell division and it restricts growth and development of explant.
Bhushan S. Bhadane, Ravindra H. Patil
doaj   +1 more source

A CD3-Specific Antibody Reduces Cytokine Production and Alters Phosphoprotein Profiles in Intestinal Tissues From Patients With Inflammatory Bowel Disease [PDF]

, 2014
NOTICE: this is the author’s version of a work that was accepted for publication in Gastroenterology. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms ...
Alegre, Andrew J. Stagg, André van Maurik, Anna Vossenkämper, Baumgart, Belmar, Capasso, Cardone, Chang, Christian Hundsrucker, Di Sabatino, Fedorak, Filipovich, Glocker, Herold, Hirsch, Kevin Page, Keymeulen, Keymeulen, Kotlarz, Lisa Das, Macdonald, Mehta, Monteleone, Monteleone, Monteleone, Pfaffl, Plevy, Prentice, Rovedatti, Sandborn, Schreiber, Theodore J. Sanders, Thomas T. MacDonald, Tran, van der Woude, Van Wauwe, Vossenkämper, Waldron-Lynch, Wiczling, Wu, Wu, Yu   +42 more
core   +1 more source

Cryopreserved Human Otic Neuronal Spheroids Self‐assemble for Functional Connectivity Analysis and Long‐term Ototoxicity Evaluation

Advanced Science, EarlyView.
This study establishes a robust and reproducible protocol for generating human otic neuronal spheroids (hONS) from cryopreserved hPSC‐derived pre‐placodal ectoderm cells. These hONS further differentiate into functional SGN‐like neurons, which extend neurite projections toward both murine hair cells and human cortical organoids, thereby forming ...
Gaoying Sun, Yukai Wang, Man Wang, Xinyue Wang, Mingming Tang, Da Li, Jianhuan Qi, Xue Wang, Shujuan Sun, Lei Chen, Weibin An, Ligang Kong, Anqi Suo, Haibo Wang, Wenwen Liu, Lei Xu   +15 more
wiley   +1 more source

Ca2+ transients are not required as signals for long-term neurite outgrowth from cultured sympathetic neurons [PDF]

, 1990
A method for clamping cytosolic free Ca2+ ([Ca2+]i) in cultures of rat sympathetic neurons at or below resting levels for several days was devised to determine whether Ca2+ signals are required for neurite outgrowth from neurons that depend on Nerve ...
Murrell, R D, Suidan, H S, Tolkovsky, A M, Walker, A E   +3 more
core   +2 more sources

tRNA‐Derived Fragment tRF‐22 Promotes Immunosuppression by Inhibiting HnRNPAB Ubiquitination in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
tRF‐22 fosters an immunosuppressive and pro‐oncogenic tumor microenvironment in ESCC by stabilizing hnRNPAB against TRIM25‐mediated ubiquitination and enhancing TGFβ2 expression, which increases PMN‐MDSCs infiltration and suppresses CD8+ T cells. Targeting tRF‐22 or blocking TGFβ signalling improves anti‐PD1 response, offering a promising therapeutic ...
Ling Pan, Xin Qin, Li Gong, Haining Liu, Bo Cheng, Jing Wang, Yajie Hu, Lingxing Zeng, Yiping Wang, Qingxu Song, Yufeng Cheng   +10 more
wiley   +1 more source

Effect of culture time and culture medium volume per explant on Gerbera jamesonii multiplication in Temporary Immersion System

Biotecnología Vegetal, 2016
In the world flower industry, Gerbera jamesonii is among the ten plants of cut flower more commercialized. The species can be propagated through seeds, vegetative and through biotechnological techniques. The latter is the most used. In order to determine
Osbel Mosqueda Frometa, Maritza M Escalona Morgado, Marcos A Daquinta Gradaille   +2 more
doaj  

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Development of adventitious buds in banana (Musa sp.) cv. Gran Naine (AAA)

Biotecnología Vegetal, 2002
Several cytokinins were studied in the culture media with the aim of induction of adventitious buds in the cv. ‘Gran Naine’. The largest explant values with development of adventitious buds were obtained when Thidiazuron (TDZ) was used in the culture ...
Lourdes R. García, Juan Pérez Ponce, Idalmis Bermúdez-Caraballoso, Pedro Orellana, Novisel Veitía, Leonardo García, Yenny Padrón, Carlos Romero   +7 more
doaj  

Targeted Inhibition of CD74+ Macrophages by Luteolin via CEBPB/P65 Signaling Ameliorates Osteoarthritis Progression

Advanced Science, EarlyView.
This study identifies CD74⁺ macrophages as key drivers of synovial inflammation in osteoarthritis (OA). The flavonoid luteolin is predicted to inhibit this pathway by blocking Nuclear Factor Kappa‐light‐chain‐enhancer of Activated B cells (NF‐κB) signaling. To enhance delivery, a targeted nanoplatform (MDSPL) is developed.
Rui Peng, Bo Yu, Lei Zhang, Zhaowen Xue, Lutian Yao, Qingjun Yang, Zitao Liu, Sizhi Wu, Yongquan Huang, Xiaofei Zheng, Huiying Guo, Songwei Huan, Tao Jiang, Huajun Wang, Yulong Wei, Tao Gui   +15 more
wiley   +1 more source

Suppression of MMP activity in bovine cartilage explants cultures has little if any effect on the release of aggrecanase-derived aggrecan fragments [PDF]

, 2009
Bijue Wang, Pingping Chen, Anne‐Christine Bay‐Jensen, M.A. Karsdal, S.H. Madsen, Bodil-Cecilie Sondergaard, Qinlong Zheng, Per Qvist   +7 more
openalex   +1 more source