Results 131 to 140 of about 67,150 (324)

Development of adventitious buds in banana (Musa sp.) cv. Gran Naine (AAA)

open access: yesBiotecnología Vegetal, 2002
Several cytokinins were studied in the culture media with the aim of induction of adventitious buds in the cv. ‘Gran Naine’. The largest explant values with development of adventitious buds were obtained when Thidiazuron (TDZ) was used in the culture ...
Lourdes R. García   +7 more
doaj  

CircTspan3 Promotes Cartilage Development Through ANNEXIN A2‐Mediated Ferroptosis and Apoptosis Inhibition and Exosome‐Mediated Paracrine Signaling

open access: yesAdvanced Science, EarlyView.
This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan   +16 more
wiley   +1 more source

Gut–Metabolome–Proteome Interactions in Age‐Related Hearing Loss: Insights from Fecal Microbiota Transplantation and Multi‐Omics Analyses

open access: yesAdvanced Science, EarlyView.
Germ‐free (GF) mice receiving fecal microbiota transplantation (FMT) reveal microbiota‐dependent effects on auditory aging. Integrated metagenomic, metabolomic and proteomic profiling maps gut–inner ear network and highlights 5‐hydroxytryptophan (5‐HTP) as a microbiota‐linked metabolic hub in age‐related hearing loss (ARHL).
Ting Yang   +12 more
wiley   +1 more source

From Natural Discovery to AI‐Guided Design: A Curated Collection of Compact Enhancers for Crop Engineering

open access: yesAdvanced Science, EarlyView.
ABSTRACT Precise transgene‐free gene upregulation remains a challenge in crop biotechnology, as conventional enhancers often exceed CRISPR‐mediated knock‐in size constraints and face regulatory hurdles. Here we establish a foundational cross‐species resource of compact transcriptional enhancers developed via STEM‐seq, a high‐throughput screening ...
Qi Yao   +14 more
wiley   +1 more source

IN VITRO PROPAGATION OF DENDROBIUM AND PHALAENOPSIS THROUGH TISSUE CULTURE FOR CONSERVATION

open access: yesAGRIVITA Journal of Agricultural Science, 2012
The studies were focused on developing an efficient and effective propagation protocol for orchid species from genera Dendrobioum and Phalaenopsis through tissue culture.
Lita Soetopo, Sri Lestari Purnamaningsih
doaj  

DR5 Governs Compound Exocytosis in Colonic Goblet Cells via TATA‐Box Binding Protein‐Dependent Bestrophin‐2 Transcriptional Regulation

open access: yesAdvanced Science, EarlyView.
DR5 knockout exhibits a thinner colonic mucus layer, leading to mild dysbiosis, increased susceptibility to Citrobacter rodentium invasion, and exacerbated epithelial injury. Mechanistically, DR5 binds transcription factor TBP, which regulates the expression of gene Best2 via its promoter.
Ying Wang   +9 more
wiley   +1 more source

Assessment of the Integrity and Function of Human Term Placental Explants in Short-Term Culture

open access: yesMethods and Protocols
Human placental explants (HPEs) culture has generated significant interest as a valuable in vitro model for studying tissue functions in response to adverse conditions, such as fluctuations in oxygen levels, nutrient availability, exposure to pathogenic ...
Carolina López-Guzmán   +3 more
doaj   +1 more source

Cidea Targeting Protects Cochlear Hair Cells and Hearing Function From Drug‐ and Noise‐Induced Damage

open access: yesAdvanced Science, EarlyView.
Acquired sensorineural hearing loss is primarily caused by the damage or loss of cochlear hair cells, induced by factors such as noise exposure and ototoxic drugs. The deficiency of apoptosis‐inducing gene Cidea in Cidea KO mice or by delivering CRISPR/SlugCas9‐HF via AAV to edit Cidea effectively alleviated hair cell damage and hearing loss caused by ...
Shasha Zhang   +14 more
wiley   +1 more source

Cascade‐Responsive MXene@Cu‐MOF Heterostructure Integrates Antioxidant Activity, Infection Control, and Vascularization for Tracheal Repair

open access: yesAdvanced Science, EarlyView.
A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo   +8 more
wiley   +1 more source

Differential Response of NORMAL and Tumour Oesophageal Explant Cultures to Radiation [PDF]

open access: diamond, 1988
Carmel Mothersill   +4 more
openalex   +1 more source

Home - About - Disclaimer - Privacy