Results 141 to 150 of about 3,657,908 (359)

Mechanical Stretch‐Induced Interlayer Coordination between MMP2 and COL17A1 Exacerbates Regenerative Exhaustion in Skin

Advanced Science, EarlyView.
Regeneration reaches a hidden limit under mechanical stretch. Prolonged tension alters dermal–epidermal communication, exhausting epidermal stem cells via MMP2–COL17A1 signaling. MMP2 inhibition by Marimastat preserves adhesion and regenerative capacity, offering a potential strategy to overcome the inherent boundaries of skin expansion.
Yidan Sun, Qili Qian, Luwen Xu, Bowen Gao, Ting Li, Yin Li, Jiayi Zheng, Qiaoyu Fu, Xi Cheng, Nuo Chen, Sijia Wang, Liang Zhang, Caiyue Liu, Qingfeng Li   +13 more
wiley   +1 more source

Explant culture of adult goldfish retina: effect of prior optic nerve crush [PDF]

, 1976
Gary E. Landreth, Bernard W. Agranoff
openalex   +1 more source

Research advancements and evaluation of multifactor‐induced murine models for gastric cancer

Animal Models and Experimental Medicine, EarlyView.
Murine models for gastric cancer. Abstract As one of the most prevalent gastrointestinal malignancies in humans, gastric cancer (GC) is often detected at an advanced stage, resulting in a poor prognosis and ranking it the fifth leading cause of cancer‐related deaths.
Yiqing Wang, Liang Zhang, Weixu Feng, Wanfeng Liu, Xiangyang Xue, Shiyu Feng   +5 more
wiley   +1 more source

Identification of optimal conditions for human placental explant culture and extracellular vesicle release. [PDF]

iScience, 2023
Tekkatte C, Lindsay SA, Duggan E, Castro-Martínez A, Hakim A, Saldana I, Zhang Y, Zhou J, Sebastian R, Liu Y, Pontigon DS, Meads M, Liu TN, Pizzo DP, Nolan J, Parast MM, Laurent LC.   +16 more
europepmc   +1 more source

Detection of latent cytomegalovirus in murine salivary and prostate explant cultures and cells [PDF]

, 1977
K S Cheung, David J. Lang
openalex   +1 more source

Dual‐Action 3D Bioprinted Scaffolds with MXene Quantum Dots for Tumor Suppression and Breast Tissue Regeneration Postmastectomy

Advanced NanoBiomed Research, EarlyView.
Four types of 3D hydrogel scaffolds—acellular, acellular with MXene quantum dots (MQDs), cellular, and cellular with MQDs—are developed for postmastectomy breast cancer therapy. Among them, the acellular MQD scaffold uniquely prevents tumor recurrence while promoting tissue regeneration, offering a dual‐function platform that may reduce reliance on ...
Damla Alkaya, Ozge Ozgenc, Ahmet Ceylan, Okan Ekim, Gamze Aykut, Leena Regi Saleth, Mehmet Altay Unal, Sadettin Er, Mesut Tez, Sanjiv Dhingra, Açelya Yilmazer   +10 more
wiley   +1 more source

Assessment of the Integrity and Function of Human Term Placental Explants in Short-Term Culture

Methods and Protocols
Human placental explants (HPEs) culture has generated significant interest as a valuable in vitro model for studying tissue functions in response to adverse conditions, such as fluctuations in oxygen levels, nutrient availability, exposure to pathogenic ...
Carolina López-Guzmán, Ana María García, Paula Marín, Ana María Vásquez   +3 more
doaj   +1 more source

A latent collagenase released by bone and skin explants in culture [PDF]

, 1971
Gilbert Vaes
openalex   +1 more source

Sponge Aquaculture Trials in the East-Mediterranean Sea: New Approaches to Earlier Ideas [PDF]

Aquaculture trials were conducted in the East Aegean Sea with Dysidea avara and Chondrosia reniformis to test the possibility of growing these sponges in the vicinity of sea-based fish farms.
Cerig, E., Gokalp, M., Gokalp, S.Z., Osinga, R., Sidri, M.   +4 more
core   +2 more sources

Loss of Tripartite Motif–Containing Protein 21 and UVB‐Induced Systemic Inflammation by Regulating DNA‐Sensing Pathways

Arthritis &Rheumatology, EarlyView.
Objective Patients with systemic lupus erythematosus (SLE) experience photosensitivity, with exposure to UVB light driving lupus flares and triggering symptoms like joint pain, fatigue, and cutaneous lesions. Although the mechanism(s) linking UVB exposure to systemic effects are unclear, type I interferons (IFNs) are known to play a role.
Gantsetseg Tumurkhuu, Graziela Perri, Richard Moore, Lihong Huo, Arati Naveen Kumar, Richard Ainsworth, Trinitee Oliver, Gabriela De Los Santos, David Gibb, Jessica Carriere, Jeong Min Yu, Rachel Abuav, Lindsy Forbess, Daniel J. Wallace, Mariko Ishimori, Wonwoo Shon, Christian Stehlik, Caroline A. Jefferies   +17 more
wiley   +1 more source