Results 151 to 160 of about 3,569,444 (365)

Cartilage‐Penetrating Framework Nucleic Acid Nanoparticles Ameliorate Osteoarthritis by Promoting Drug Delivery and Chondrocyte Uptake

Advanced Science, EarlyView.
Based on the poor cartilage penetration of tFNA, a novel tFNA‐2WL with excellent cartilage permeability and perfect chondrocyte endocytosis properties is designed and fabricated. As a result, tFNA‐2WL has a nearly seven‐fold increase in the penetration depth into the cartilage, with the same excellent cell entry properties as tFNA.
Kui Huang, Qiumei Li, Huixuan Lin, Qian Shen, Yaping Wu, Taoran Tian, Chuan Ma, Sirong Shi, Jingang Xiao, Yunfeng Lin   +9 more
wiley   +1 more source

Increased regeneration efficiency of _Brassica napus_ L. cultivars Star, Westar and Cyclone from hypocotyle and cotyledonary explants [PDF]

, 2010
The comparative organogenesis of _Brassica napus_ L cultivars Cyclone, Star and Westar was studied. The cotyledonary explants gave a higher response to all the combinations of 0.5 mg/L 2,4-D and BAP (0.5, 1.0,1.5 and 2.0 mg/L} used for optimizing the ...
Arfa Farooqi, Israr Khan, Muhammadwaheed Akhtar, Sikandar Khan, Waqar Ali, Zahir Ali Takar   +5 more
core   +1 more source

Effect of culture time and culture medium volume per explant on Gerbera jamesonii multiplication in Temporary Immersion System

Biotecnología Vegetal, 2016
In the world flower industry, Gerbera jamesonii is among the ten plants of cut flower more commercialized. The species can be propagated through seeds, vegetative and through biotechnological techniques. The latter is the most used. In order to determine
Osbel Mosqueda Frometa, Maritza M Escalona Morgado, Marcos A Daquinta Gradaille   +2 more
doaj  

Destructive effects of murine arthritogenic antibodies to type II collagen on cartilage explants in vitro [PDF]

, 2005
Certain monoclonal antibodies (mAbs) to type II collagen (CII) induce arthritis in vivo after passive transfer and have adverse effects on chondrocyte cultures and inhibit self assembly of collagen fibrils in vitro.
Crombie, Duncan E, Holmdahl, Rikard, McNaughton, Don, Nandakumar, Kutty Selva, Rowley, Merrill J, Turer, Muhammed, Van Damme, Marie-Paule, Wood, Bayden, Zuasti, Beltzane Biurrun   +8 more
core   +2 more sources

Functional Synovium‐Based 3D Models in the Context of Human Disease and Inflammation

Advanced NanoBiomed Research, EarlyView.
The synovium is key to joint function but is often affected by diseases like rheumatoid arthritis. Finding better treatments is challenging because current lab models do not fully mimic real tissues. New 3D technologies, like bioprinting, offer better methods to study these diseases, improve drug testing, and develop personalized treatments, bringing ...
Amelia Heslington, Catharien M. U. Hilkens, Ana Marina Ferreira, Priscila Melo   +3 more
wiley   +1 more source

Development of adventitious buds in banana (Musa sp.) cv. Gran Naine (AAA)

Biotecnología Vegetal, 2002
Several cytokinins were studied in the culture media with the aim of induction of adventitious buds in the cv. ‘Gran Naine’. The largest explant values with development of adventitious buds were obtained when Thidiazuron (TDZ) was used in the culture ...
Lourdes R. García, Juan Pérez Ponce, Idalmis Bermúdez-Caraballoso, Pedro Orellana, Novisel Veitía, Leonardo García, Yenny Padrón, Carlos Romero   +7 more
doaj  

Effect of Incubation Periods, Medium Volumes and Explants Density on in Vitro Shoot Formation and Growth and Cost of Multiplication of Moris Pineapple (Ananas comosus L.)

مجلة المختار للعلوم, 2018
This study was conducted to investigate the effect of combinations of four incubation periods (30, 45, 60 and 75 days), three explants density (one, two and three) and four volumes of medium (3, 6, 9 and 12 ml) in the in vitro shoot formation per ...
Abdelhamid A. Hamad
doaj   +1 more source

Decoding regulatory programs underlying placode and dermal condensate cell fate commitment during hair follicle induction via single‐cell multi‐omics analysis

Animal Research and One Health, EarlyView.
The experimental framework of the study encompasses sample collection, single‐cell data analysis, and experimental validation. Abstract Understanding differences in chromatin state and changes in gene regulatory landscape of placode (Pc) and dermal condensate are crucial for decoding hair follicle (HF) morphogenesis programs.
Fang Li, Minghao Li, Tongtong Zhang, Menghua Sui, Hasan Khatib, Xin Wang   +5 more
wiley   +1 more source

Development of hydroxyapatite-coated nonwovens for efficient isolation of somatic stem cells from adipose tissues

Regenerative Therapy, 2022
Adipose-derived stem cells (ASCs) are an attractive cell source for cell therapy. Despite the increasing number of clinical applications, the methodology for ASC isolation is not optimized for every individual.
Ryota Chijimatsu, Taiga Takeda, Shinsaku Tsuji, Kohei Sasaki, Koichi Kato, Rie Kojima, Noriko Michihata, Toshiya Tsubaki, Aya Matui, Miharu Watanabe, Sakae Tanaka, Taku Saito   +11 more
doaj  

Association of Synovial Innate Immune Exhaustion With Worse Pain in Knee Osteoarthritis

Arthritis &Rheumatology, EarlyView.
Objective Uncontrolled pain remains a major clinical challenge in the management of knee osteoarthritis (OA), the most common disabling joint disease. Worse pain is associated with synovial innate immune cell infiltration (synovitis), but the role of innate immune‐regulatory cells in pain is unknown. Our objective was to identify synovial innate immune
Holly T. Philpott, Trevor B. Birmingham, Garth Blackler, J. Daniel Klapak, Alexander J. Knights, Easton C. Farrell, Benoit Fiset, Logan A. Walsh, J. Robert Giffin, Edward M. Vasarhelyi, Steven J. MacDonald, Brent A. Lanting, Tristan Maerz, C. Thomas Appleton, on behalf of the WOREO Knee Study Group   +14 more
wiley   +1 more source