A novel human donor cornea preservation cocktail incorporating a thermo-reversible gelation polymer (TGP), enhancing the corneal endothelial cell density maintenance and explant culture of corneal limbal cells. [PDF]
Biotechnol Lett, 2021 Namitha B +11 more
europepmc +1 more source
Somatic embryos formation from immature cotyledons in Phaseolus vulgaris cv. CIAP 7247
Biotecnología Vegetal, 2011 Common bean, like most of legumes, is recalcitrant to in vitro culture, so the establishment of a regeneration procedure via somatic embryogenesis in this specie has not been possible.
Raúl Collado +6 more
doaj
Aging Cell, EarlyView.The authors' research shows that CARM1 regulates cartilage degeneration in osteoarthritis through the ERK1/2 signaling pathway, suggesting its potential as a therapeutic target and providing valuable insights into the mechanisms of cartilage degradation and inflammation in the disease.
Jie Yuan +9 more
wiley +1 more source
The Flowering of Sunflower Explants in Aseptic Culture [PDF]
Plant Physiology, 1954 openaire +3 more sources
Aging Cell, EarlyView.βA3/A1‐crystallin regulates HDAC3 activity and epigenetic processes in the RPE. (A) The illustration demonstrates that βA3/A1‐crystallin plays a crucial role in maintaining IPMK protein expression, which in turn activates HDAC3. (B) When βA3/A1‐crystallin is absent (Cryba1 KO ), IPMK protein expression decreases, resulting in the deactivation of HDAC3.
Sujan Chatterjee +16 more
wiley +1 more source
Dexamethasone is a regulator of clock genes in testicular peritubular cells
Andrology, EarlyView.Abstract Background We recently found that peritubular cells of the human testis are a dominant site of expression of the glucocorticoid receptor (GR; encoded by NR3C1). Activation of GR by dexamethasone (Dex) strongly influences the phenotype of cultured human testicular peritubular cells (HTPCs), causing massive changes of their proteome and ...
Harald Welter +11 more
wiley +1 more source
Plasmid/liposome transfer of the human manganese superoxide dismutase transgene prevents ionizing irradiation-induced apoptosis in human esophagus organ explant culture [PDF]
, 2000 Michael W. Epperly +7 more
openalex +1 more source
An in vitro ovarian explant culture system to examine sex change in a hermaphroditic fish. [PDF]
PeerJ, 2020 Goikoetxea A +5 more
europepmc +1 more source
Opportunities of patient‐derived organoids in drug development
British Journal of Pharmacology, EarlyView.Various model systems are utilised during drug development starting from basic research, moving to preclinical research and development for clinical applications in order to identify new drugs to improve human health. However, there are characteristics of humans that are not captured by established models.
Antonia Büning, Elena Reckzeh
wiley +1 more source