Uncoupling TGFβ1 signalling from collagen protein synthesis in Dupuytren's disease
Abstract Dupuytren's disease is a fibroproliferative disorder of the palmer fascia (PF) characterised by flexion contractures in the hand. Dupuytren's disease can be treated surgically, but disease recurrence rates are high, potentially due to continual production of matrisomal proteins.
Gabriella Cooper +12 more
wiley +1 more source
Transcriptional Analysis by Nascent RNA FISH of <em>In Vivo</em> Trophoblast Giant Cells or <em>In Vitro</em> Short-term Cultures of Ectoplacental Cone Explants [PDF]
C. Corbel, Édith Heard
openalex +1 more source
Migrasomes, Matrix‐Bound Nanovesicles, and More: Messengers in the Matrix
ABSTRACT Extracellular vesicles (EVs) and particles (EPs) are diverse micro‐ and nanoparticles that circulate in bodily fluids and can attach to, or be deposited onto, the extracellular matrix (ECM) and other surfaces. To date, the nomenclature and classification of matrix‐bound or matrix‐associated EVs and EPs (MEVPs) have been unclear, largely due to
Anna V. Kolesov +3 more
wiley +1 more source
Influence of polysulfated glycosaminoglycan on equine articular cartilage in explant culture [PDF]
John P. Caron +2 more
openalex +1 more source
Engineering compact Physalis peruviana (goldenberry) to promote its potential as a global crop
Goldenberry (Physalis peruviana) produces sweet, nutritionally rich berries, yet like many minor crops, is cultivated in limited geographical regions and has not been a focus of breeding programs for trait enhancement. Leveraging knowledge of plant architecture‐related traits from related species, we used CRISPR/Cas9‐mediated gene editing to generate a
Miguel Santo Domingo +8 more
wiley +1 more source
Cigarette smoke extract exacerbates progression of osteoarthritic‐like changes in cartilage explant cultures [PDF]
Emily Sawvell +5 more
openalex +1 more source
ABSTRACT The limited osteogenic capacity of magnesium phosphate cement (MPC) has constrained its biomedical applications, underscoring the necessity to develop MPC with enhanced physical properties and bone‐forming capabilities. In this study, a multifunctional MPC system was developed by incorporating zoledronic acid‐loaded near‐infrared (NIR ...
Bin Wang +8 more
wiley +1 more source
Tissue Culture Propagation of Olive (Olea europaea L.) cv. Jlott by Using Shoot Tip: 2-Effect of Different Hormones on The Growth and Rooting of The Explants in the Multiplication and Rooting Phases [PDF]
Ala din Jarad +2 more
openalex +1 more source
We introduce a versatile 3D platform that recreates key physical and biological features of the human bone marrow. By integrating tunable silk biomaterials, stromal cells, and human hematopoietic progenitors, the model captures both healthy and diseased microenvironments, analysis of blood formation, and its disruption in pathological conditions ...
Christian A. Di Buduo +13 more
wiley +1 more source

