Results 221 to 230 of about 3,692,560 (357)

3D Quantification of Viral Transduction Efficiency in Living Human Retinal Organoids

open access: yesSmall Methods, EarlyView.
Optimization of viral vectors and their testing in human tissue is crucial to gene therapy development. Conventional technologies to assess virus transduction either lack spatial or temporal information. Here, spatiotemporal mapping of virus transduction in living retinal tissue is introduced, levering fluorescence imaging and machine learning‐based ...
Teresa S. Rogler   +11 more
wiley   +1 more source

Comparative temporal transcriptome analyses of SARS-CoV-2 delta and omicron variants ex-vivo infection in cat lung explant culture. [PDF]

open access: yesFront Cell Infect Microbiol
Panwar A   +10 more
europepmc   +1 more source

An in vitro ovarian explant culture system to examine sex change in a hermaphroditic fish. [PDF]

open access: yesPeerJ, 2020
Goikoetxea A   +5 more
europepmc   +1 more source

Agents that Activate Cyclic AMP-Dependent Protein Kinase Inhibit Explant Culture Growth and Mitotic Activity

open access: bronze, 1983
Kenneth M. Halprin   +5 more
openalex   +1 more source

Mono(2‐Ethylhexyl) Phthalate Induces Inflammatory and Angiogenic Alterations Mediated by the PI3K/AKT Pathway in HTR‐8/SVneo Trophoblastic Cells

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Exposure to mono(2‐ethylhexyl) phthalate (MEHP) during pregnancy has been associated with adverse pregnancy and birth outcomes characterized by extravillous trophoblast (EVT) abnormal function. Previous reports have suggested that MEHP can activate the PI3K/AKT pathway in EVT cells, a pathway known to regulate inflammation and angiogenesis in ...
Luis Daniel Martínez‐Razo   +5 more
wiley   +1 more source

Prolonged airway explant culture enables study of health, disease, and viral pathogenesis. [PDF]

open access: yesSci Adv
Lee-Ferris RE   +20 more
europepmc   +1 more source

Integrated multi‐omics analysis reveals metabolic reprogramming as a key driver of angiotensin II‐induced vascular remodeling

open access: yesVIEW, EarlyView.
This study investigates the molecular alterations underlying angiotensin II (Ang II)‐induced vascular remodeling in cardiovascular diseases using a multi‐omics approach. Through data exploration and integrated multi‐omics analysis, our findings reveal that Ang II‐driven vascular injury in vascular smooth muscle cells is mediated by metabolic ...
Yiwei Hu   +8 more
wiley   +1 more source

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