Results 251 to 260 of about 3,692,560 (357)

Zebrafish as a model for Catel–Manzke syndrome—identification and characterization of the zebrafish TGDS ortholog

open access: yesThe FEBS Journal, EarlyView.
Zebrafish Tgds, when expressed as a recombinant protein, catalyzes the dehydration of UDP‐D‐glucose, the initial step in the formation of 6‐deoxyhexoses. Corresponding Tgds mutations found in Catel–Manzke syndrome patients lead to reduced enzymatic activity and stability.
Maria Rosaria Coppola   +11 more
wiley   +1 more source

A novel approach to target skin photodamage: Topical application of salt inducible kinase inhibitors

open access: yesInternational Journal of Cosmetic Science, EarlyView.
UV‐induced photodamage leads to increased DNA damage and elevated MMP levels, which degrade collagen and contribute to wrinkle formation. SLT‐001 and SLT‐008, novel cosmetic ingredients that target salt‐inducible kinase, help reverse this effect by enhancing DNA repair, reducing MMP expression and decreasing erythema, thereby mitigating photodamage ...
Inbal Rachmin   +7 more
wiley   +1 more source

Bacterial porphyrins in healthy skin: Microbiota components impact melanogenesis and age‐related processes leading to Porphyr'ageing

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Porphyrins, previously linked only to acne inflammation, are now implicated in skin ageing. Their presence correlates with increased melanin, inflammation, and oxidative stress, contributing to premature ageing signs. This study introduces the concept of “Porphyr'ageing,” highlighting the detrimental effects of bacterial metabolites on skin health and ...
Marie Meunier   +9 more
wiley   +1 more source

Antioxidative and chaperone‐like activities of a bacterioruberin‐rich extract: An innovative approach to protect the skin proteome

open access: yesInternational Journal of Cosmetic Science, EarlyView.
The bacteriorubin‐rich extract of Arthrobacter agilis has high antioxidative properties, protecting proteins against oxidative stress and preventing their carbonylation. It also protects proteins against saline and heat stresses, suggesting a dual mode of action including antioxidant and chaperone‐like activities.
Julie C. Tisserand   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy