Results 281 to 290 of about 66,082 (347)

Can the choice of artificial tears harm patients? A narrative review with an overview of the Nordic market

Acta Ophthalmologica, Volume 103, Issue 5, Page 586-608, August 2025.
Abstract Purpose To provide an overview of artificial tears marketed in the following Nordic countries: Denmark, Finland, Norway, Iceland and Sweden. Furthermore, this review aimed to highlight the different preservatives and other constituents found in artificial tears in the Nordic market, focussing on adverse effects.
K. N. Mikha, C. E. Ø. Rasmussen, S. N. G. Ahrensberg, J. Freiberg, R. A. Wozniak, U. M. K. Alnoor, F. Fineide, T. P. Utheim, S. Heegaard, M. Kolko   +9 more
wiley   +1 more source

Models of Endocrine‐Disrupting Effects: Human Placental Steroidogenesis

Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 2, August 2025.
ABSTRACT Endocrine disruption during pregnancy has gained increasing interest as epidemiological studies report associations of exposures and adverse effects on fetal growth, followed by effects on the growing child and ultimately in the adult. When studying endocrine disruption during pregnancy, the placental steroidogenesis is difficult to model, as ...
Line Mathiesen, Dea Sandal, Ida Elise Moelgaard Hammer, Bjarne Styrishave, Lisbeth E. Knudsen   +4 more
wiley   +1 more source

Evaluation of Rasna panchaka (indigenous drug) as oxidative stress down-regulator using serum-free explant culture system.

Indian J Pharmacol, 2018
Talluri M, Yathapu SR, Bharatraj DK.
europepmc   +1 more source

Activation of autophagy mediated by PI3K/Akt/mTOR signalling cascade alleviates impaired adipose‐derived stem cell osteogenesis in a diabetic microenvironment

British Journal of Pharmacology, Volume 182, Issue 15, Page 3522-3538, August 2025.
Abstract Background and Purpose Advanced glycation end products (AGEs) contribute to the onset and advancement of diabetic osteoporosis (DOP). Adipose‐derived stem cells (ASCs) have garnered attention in the field of bone renewal; the mechanisms leading to decreased osteogenesis within a diabetic environment are not fully understood.
Fangzhi Lou, Ting Fu, Qilin Li, Pengcheng Rao, Shuanglin Peng, Shi Lu, Tianli Wu, Qing Li, Jingang Xiao   +8 more
wiley   +1 more source

Transcriptional evidence of pluripotency during development of the leaf gall formed by grape phylloxera (Daktulosphaira vitifoliae)

New Phytologist, Volume 247, Issue 4, Page 1712-1726, August 2025.
Summary Galls are structures formed by plants in response to stimuli by parasitic insects. Because galls require altered gene expression to change cell fates, their initiation requires pluripotent or ‘reactive’ cells. We used RNA sequencing to test three hypotheses about potential sources of pluripotency in the leaf gall formed by grape phylloxera ...
Jack C. Schultz, Mélanie J. A. Body, Patrick P. Edger, Sarah Melissa Witiak, Heidi M. Appel   +4 more
wiley   +1 more source

Unstable anthocyanin pigmentation in Streptocarpus sect. Saintpaulia (African violet) is due to transcriptional selectivity of a single MYB gene

New Phytologist, Volume 247, Issue 3, Page 1426-1444, August 2025.
Summary Saintpaulia (African violet) pigmentation is notoriously unstable and sometimes forms white stripes, particularly following passage through tissue culture. White‐striped petals were thought to be due to periclinal chimeras, but we confirmed that white stripes result from epigenetic regulation rather than periclinal chimeras based on the flower ...
Daichi Kurata, Tomohisa Tsuzaki, Fumi Tatsuzawa, Kenta Shirasawa, Hideki Hirakawa, Munetaka Hosokawa   +5 more
wiley   +1 more source

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

Molecular Oncology, Volume 19, Issue 7, Page 2133-2143, July 2025.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens, Anouk Mentink, Frank A. W. Coumans, Eshwari Dathathri, Khrystany T. Isebia, Jaco Kraan, Ronald de Wit, John W. M. Martens, Leon W. M. M. Terstappen   +8 more
wiley   +1 more source

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

Advanced Biology, Volume 9, Issue 7, July 2025.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim, Kanghoon Choi, Amy Lin, Jungkyu Kim   +3 more
wiley   +1 more source

Recent Advances in Stimuli‐Responsive Materials and Soft Robotic Actuators for Bioelectronic Medicine

Advanced Materials, Volume 37, Issue 27, July 10, 2025.
This review explores the integration of responsive materials and soft robotic actuators with implantable electronics to address key challenges in bioelectronic medicine. By enabling shape actuation, these technologies improve deployment, adaptability, and accuracy in minimally invasive procedures.
Chaoqun Dong, George G. Malliaras
wiley   +1 more source

Emerging Therapeutic Strategies for Hearing Loss

Advanced Therapeutics, Volume 8, Issue 7, July 2025.
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han, Tian Shen, Weiwei He, Hao Wei, Xiaolong Zhao, Wen Yang, Chuan Bu, Xinghua Tang, Yu Zhao, Jiangang Fan   +9 more
wiley   +1 more source