Results 291 to 300 of about 3,657,908 (359)

Spiral Ganglion Neuron Explant Culture and Electrophysiology on Multi Electrode Arrays. [PDF]

J Vis Exp, 2016
Hahnewald S, Roccio M, Tscherter A, Streit J, Ambett R, Senn P.   +5 more
europepmc   +1 more source

New Integrative Vectors Increase Agrobacterium rhizogenes Transformation and Help Characterise Roles for Soybean GmTML Gene Family Members

Plant, Cell &Environment, EarlyView.
ABSTRACT Hairy‐root transformation is widely used to generate transgenic plant roots for genetic functional characterisation studies. However, transformation efficiency can be limited, largely due to the use of binary vectors. Here, we report on the development of novel integrative vectors that significantly increase the transformation efficiency of ...
Huanan Su, Mengbai Zhang, Estelle B. Grundy, Brett J. Ferguson   +3 more
wiley   +1 more source

A skin explant model for studying UV‐induced DNA damage and repair

Photochemistry and Photobiology, EarlyView.
The study describes an ex vivo skin model that preserves the natural physiology of the skin while addressing ethical concerns related to animal research. We demonstrate this model maintains key characteristics and physiological responses of in vivo skin during short incubation periods. Moreover, this model requires fewer mice than in vivo testing, thus
Hailey Payne, Christina Athans, Shiyong Wu, Veronica Bahamondes Lorca   +3 more
wiley   +1 more source

P298 The isoforms of ADAMTS-4 and -5 vary with IL-1 dose in explant cultures

, 2005

openalex   +1 more source

Constitutive nitric oxide synthases deficiency impairs cyclobutane pyrimidine dimer repair following solar UV exposure in cells and mice

Photochemistry and Photobiology, EarlyView.
Proposed model for the dual role of cNOS in DNA damage and repair upon UV radiation. Abstract Solar ultraviolet (sUV) radiation is a major environmental factor that induces DNA damage, promoting skin aging and carcinogenesis. The formation of cyclobutane pyrimidine dimers (CPDs) is one of the most prevalent forms of UV‐induced DNA lesions, playing a ...
Veronica Bahamondes Lorca, Yuxi Zhou, Christina Athans, Hailey Payne, Madison Wright, Zeinab Feyyaz, Lingying Tong, Dawn L. Sammons, Shiyong Wu   +8 more
wiley   +1 more source

Duckweeds: Model organisms for research on plant sterols and steroids

Plant Biology, EarlyView.
Duckweeds (Lemnaceae), the fastest‐growing angiosperms and promising vegan protein source, offer a powerful model to address key questions in plant physiology. This article highlights their potential for dissecting the biosynthesis and function of phytosterols, sterol conjugates, brassinosteroids, and specialized steroidal metabolites, such as ...
J. Klein, K.‐J. Appenroth, K. S. Sree
wiley   +1 more source

Protein/peptide transduction in metanephric explant culture. [PDF]

Methods Mol Biol, 2014
Plisov S, Wang H, Tarasova N, Sharma N, Perantoni AO.   +4 more
europepmc   +1 more source

Reviewing the benefits and clinical outcomes of oral fibroblasts over mesenchymal stem cells for repairing periodontal defects during or after orthodontic tooth movement

Periodontology 2000, EarlyView.
Abstract Orthodontic therapy applies forces to teeth, causing an inflammatory reaction in the periodontal ligament. This is repaired by remodeling of the periodontium, allowing tooth displacement. Although orthodontic therapy is mostly initiated during childhood and adolescence, the number of adults seeking this treatment is increasing as our society's
Ludovica Parisi, Eleni Mavrogonatou, Anton Sculean, Dimitris Kletsas, Martin Degen   +4 more
wiley   +1 more source

Endothelial‐to‐mesenchymal transition in the fetoplacental macrovasculature and microvasculature in pregnancies complicated by gestational diabetes

The Journal of Physiology, EarlyView.
Abstract figure legend Transforming growth factor (TGF)‐β2 and interleukin (IL)‐1β induced morphological and molecular changes consistent with endothelial‐to‐mesenchymal transition (EndMT) in HUVECs isolated from both pregnancies complicated by gestational diabetes (GDM) and non‐GDM pregnancies.
Abigail R. Byford, Georgia Fakonti, Ziyu Shao, Sharanam Soni, Sophie L. Earle, Muath Bajarwan, Lara C. Morley, Beth Holder, Eleanor M. Scott, Karen Forbes   +9 more
wiley   +1 more source

A Genotype‐Independent Transformation and Gene‐Editing System for Populus

Plant Biotechnology Journal, EarlyView.
Jiaxing Zhang, Xun Tang, Mengqi Sun, Chang Liu, Hasi Yu   +4 more
wiley   +1 more source