Results 91 to 100 of about 1,180,576 (325)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Transformers and Attention: Decoding and Understanding of Aspect-Based Opinions in User-Generated Contents

IEEE Access
Aspect-based opinion mining has become a significant information extraction technique based on natural language processing, driven by the growing volume of online user-generated content.
Satarupa Biswas, G. Poornalatha
doaj   +1 more source

Multi Layered Rule-Based Technique for Explicit Aspect Extraction from Online Reviews [PDF]

, 2022
Mubashar Hussain, Toqir A. Rana, Aksam Iftikhar, Muhammad Usman Ashraf, Muhammad Waseem Iqbal, Ahmed Alshaflut, Abdullah Alourani   +6 more
openalex   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Gas Permeation Model of Mixed-Matrix Membranes with Embedded Impermeable Cuboid Nanoparticles

Membranes, 2020
In the packaging industry, the barrier property of packaging materials is of paramount importance. The enhancement of barrier properties of materials can be achieved by adding impermeable nanoparticles into thin polymeric films, known as mixed-matrix ...
Haoyu Wu, Maryam Zamanian, Boguslaw Kruczek, Jules Thibault   +3 more
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Sparse Attention-Based Residual Joint Network for Aspect-Category-Based Sentiment Analysis

Mathematics
Aspect-based sentiment analysis (ABSA) aims at identifying the sentiment polarity for a particular aspect in a review. ABSA studies based on deep learning models have exploited the attention mechanism to detect aspect-related parts.
Jooan Kim, Hyunyoung Kil
doaj   +1 more source

Engineered spin phase diagram of two interacting electrons in semiconductor nanowire quantum dots

, 2009
Spin properties of two interacting electrons in a quantum dot (QD) embedded in a nanowire with controlled aspect ratio and longitudinal magnetic fields are investigated by using a configuration interaction (CI) method and exact diagonalization (ED ...
Chen, Yan-Ting, Cheng, Shun-Jen, Tang, Chi-Shung   +2 more
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Syntactic-Guided Chain of Thought for Iterative Implicit and Explicit Target Detection in Aspect-Based Sentiment Analysis

IEEE Access
Prompt engineering is essential for optimizing the performance of large-language models (LLMs), particularly in tasks requiring complex interpretations such as aspect-based sentiment analysis (ABSA).
Mohammad Radi, Nazlia Omar, Wandeep Kaur
doaj   +1 more source