Results 91 to 100 of about 1,195,586 (290)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

An operator expansion for integrable quantum field theories

open access: yes, 2013
A large class of quantum field theories on 1+1 dimensional Minkowski space, namely, certain integrable models, has recently been constructed rigorously by Lechner.
Babujian H M   +17 more
core   +1 more source

Extracting Explicit and Implicit Aspects Using Deep Learning

open access: yesEmerging Science Journal
The proliferation of user-generated content on social networks and websites has heightened the significance of sentiment analysis, also known as opinion mining, as a critical tool for comprehending people’s attitudes toward various topics. Aspect-level sentiment analysis, which considers specific aspects or features of texts, provides a more ...
Mikail Muhammad Azman Busst   +3 more
openaire   +3 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Engineered spin phase diagram of two interacting electrons in semiconductor nanowire quantum dots

open access: yes, 2009
Spin properties of two interacting electrons in a quantum dot (QD) embedded in a nanowire with controlled aspect ratio and longitudinal magnetic fields are investigated by using a configuration interaction (CI) method and exact diagonalization (ED ...
Chen, Yan-Ting   +2 more
core   +1 more source

Multi-Level Knowledge Engineering Approach for Mapping Implicit Aspects to Explicit Aspects [PDF]

open access: yesComputers, Materials & Continua, 2022
Jibran Mir   +2 more
openaire   +1 more source

Aspects of integration of explicit and implicit knowledge in connectionist expert systems

open access: yesICONIP'99. ANZIIS'99 & ANNES'99 & ACNN'99. 6th International Conference on Neural Information Processing. Proceedings (Cat. No.99EX378), 1999
A unified approach for integrating explicit and implicit knowledge in connectionist expert systems is proposed. The explicit knowledge is represented by discrete fuzzy rules, which are directly mapped into an equivalent multi-purpose neural network based on the MAPI neuron (A.F. Rocha et al., 1992).
Neagu, D, Negoita, M, Palade, V
openaire   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

On the first Zassenhaus conjecture for integral group rings

open access: yes, 2004
It was conjectured by H. Zassenhaus that a torsion unit of an integral group ring of a finite group is conjugate to a group element within the rational group algebra.
Bovdi, V., Höfert, C., Kimmerle, W.
core   +1 more source

Home - About - Disclaimer - Privacy