Results 91 to 100 of about 6,941,943 (289)
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
An Explicit Formula for Local Densities of Quadratic Forms
Let \(S\) and \(T\) be two integral nondegenerate symmetric matrices of \(\mathbb{Z}_p\) of degree \(m\) and \(n\) respectively. Assume \(m>n\geq 1\). Then the local density of representing \(T\) by \(S\) is defined as \[ \alpha_p(T,S)=\lim_{t\to\infty}(p^t)^{n(n+1)/2-mn}A_t(T,S), \] where \(A_t(T,S)=\sharp\{X\in M_{m,n}(\mathbb{Z}_p/p^t):X^tSX\equiv T\
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In fra mework of the geometrical diffraction theory, the explicit expressions for the pre s sure in waves arbitrarily re reflected N times from a contour, boundary surfaces of the cylindrical and spherical refle c tors are obtained.
N. V. Boyev +2 more
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Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
An explicit form of the inverse of a particular circulant matrix
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
Refining urban typologies: causal insights into urban form, car commuting, and related CO2 emissions
Urban transport is a major source of greenhouse gas emissions, making effective urban planning crucial for climate mitigation. Global typologies of cities can help to scale planning strategies, yet they hardly capture how interventions translate into ...
Felix Wagner +8 more
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source

