Results 111 to 120 of about 15,855,114 (308)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
On explicit forms for ergodicity coefficients
Linear Algebra and its Applications, 1993 Suppose \(\| \cdot \|\) is any vector norm on row vectors constituting \(\mathbb{R}^ n\), and \(S_ n\) \((n \geq 2)\) the set of all \(n \times n\) stochastic matrices. The definition of an ergodicity coefficient \(\tau\) for \(P=\{p_{ij}\}\), \(P \in S_ n\) with respect to the norm \(\| \cdot \|\) is \(\tau(P)=\sup \{\| {\underset \sim x}^ T P ...
openaire +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Explicit computation of the Chern character forms [PDF]
Geometriae Dedicata, 2015 14 pages, reference added, typos corrected.
openaire +2 more sources
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
IET Control Theory & ApplicationsThis paper proposes explicit solutions for the algebraic Riccati matrix equation. For single‐input systems in controllable canonical form, the explicit Hermitian solutions of the non‐homogeneous Riccati equation are obtained using the entries of the ...
Liangyin Zhang +3 more
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A Formulation of an Evolution Equation Governing Magnetic Lines
Journal of Optimization, Differential Equations and Their Applications, 2018 It is shown that `a free function' in the evolution equation of Hornig & Schindler for the magnetic induction (Physics of Plasmas, 3 (3), 781 - 791) has a unique representation, obtained in an explicit form.
Vladimir L. Borsch
doaj +1 more source