Results 121 to 130 of about 6,941,943 (289)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Differential effects of explicit form-focused instruction on morphosyntactic development
, 2017 This study explores whether and to what degree explicit form-focused instruction (FFI) facilitates the use of morphosyntactic forms in second language oral production and also whether it has differential effects on morphosyntactic forms with different ...
Lyster, Roy, Xu, Hainu
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
An Explicit Theta Lift to Siegel Paramodular Forms
Abstract Let E / L be a real quadratic extension of number fields. We construct an explicit map from an irreducible cuspidal automorphic representation of $$\mathop ...
Johnson-Leung, Jennifer, Rupert, Nina
openaire +2 more sources
Using Cross-Lingual Explicit Semantic Analysis for Improving Ontology Translation [PDF]
, 2012 Semantic Web aims to allow machines to make inferences using the explicit conceptualisations contained in ontologies. By pointing to ontologies, Semantic Web-based applications are able to inter-operate and share common information easily.
Asooja, Kartik +3 more
core
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Systolic arrays for group explicit methods for solving parabolic partial differential equations
, 1988 A systolic array implementation for solving parabolic equations numerically is presented. The finite-difference methods used are stable asymmetric approximations to the partial differential equations, which when coupled in groups of two adjacent points ...
Megson, G.M., Evans, D.J.
core +1 more source
Higher-order approximations for space-fractional diffusion equation
Journal of Numerical Analysis and Approximation TheorySecond-order and third-order finite difference approximations for fractional derivatives are derived from a recently proposed unified explicit form. The Crank-Nicholson schemes based on these approximations are applied to discretize the space-fractional
Anura Gunarathna Wickramarachchi +1 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
An explicit form of the polynomial part of a restricted partition function. [PDF]
Res Number Theory, 2017 Dilcher K, Vignat C.
europepmc +1 more source