Results 131 to 140 of about 2,325,301 (352)

Teaching talk, tell-backs, and a declarative to procedural knowledge interface [PDF]

, 2016
Can explicit, declarative knowledge be converted to implicit, procedural knowledge? This Teaching Tip advocates the use of Teaching Talk, defined as succinct and therefore retrievable language of instruction, restated by learners as Tell-Backs for the ...
Reed, Marnie
core  

UTILIZATION OF EXPLICIT INSTRUCTION IN KINDERGARTEN

European Journal of Education Studies
This study aimed to determine the effectiveness of utilizing explicit instruction in kindergarten at P. Kindat Elementary School in the school year 2022-2023. The researcher utilized a non-equivalent group quasi-experimental design because the learners were grouped heterogeneously for which random selection and assignment were not possible.
Jobelyn L. Cadungog, Cornelio R. Rollo
openaire   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Explicit vs. Contrastive-based Instruction of Formulaic Expressions in Developing EFL Learners’ Reading Ability [PDF]

Journal of Applied Linguistics, 2012
As an integrative component of textual structure, formulaic expressions (FEs) play a key role in communicating the message and comprehending the text. Furthermore, interlingually contrastive features of FEs add to their both significance and complexity ...
Gholam-Reza Abbasian, Seyeed Jalil Ehsanian   +1 more
doaj  

Teaching Future School Personnel to Train Parents to Implement Explicit Instruction Interventions. [PDF]

Behav Anal Pract, 2021
Kupzyk S, LaBrot ZC.
europepmc   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Accessing Background Knowledge To Build Mathematical Vocabulary [PDF]

, 2007
This paper examines the benefits of accessing knowledge to build background knowledge in mathematics. Various methods of vocabulary instruction are explained and examined.
Sodeman, Stephanie
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

The Effects of Explicit Grammar Instruction on the Learning of Simple and Complex Grammar Rules

Revue des Sciences Humaines, 2015
This study examines the effects of explicit instruction on learning simple and complex rules. While the target simple rule underlies the optional inversion of subject and verb following fronting of adverb of place, the two target complex rules underlie ...
Karima BELKACEM-BOURICHA
doaj  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source