Results 121 to 130 of about 1,127,197 (289)

The Effect of Explicit and Implicit Instruction on Learning and Retention of Metaphor-based Economic Terms

open access: yesNaqd-i Zabān va Adabīyyāt-i Khārijī, 2017
The purpose of this study was to investigate the effect of explicit and implicit instruction on learning and retention of metaphor-based economic terms on the part of Iranian language learners of Economics.
عادله حیدری   +2 more
doaj  

The effect of implicit and explicit motor learning on a targeting task in children with autism spectrum disorder (ASD)

open access: yesActa Psychologica
This study aims to investigate the effect of different implicit and explicit instructions on learning a fundamental motor skill (throwing task) in autistic children with a high propensity for reinvestment.
Morteza Homayounnia Firouzjah   +2 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Leveling the Field: The Need for Explicit Instruction of Argumentative Form for 'Struggling' Secondary Students

open access: yes, 2009
In this essay, a method for explicit teaching of argumentative form is purported, based on the methods of classical rhetoric. Throughout, it argues that the secondary student labeled "struggling" is often one who is a cultural minority and who ...
Bado-Aleman, Jennifer
core   +1 more source

Getting Explicit Instruction Right

open access: yes
There has been substantial public debate about the potentially deleterious effects of the long-run move to ``inquiry-based learning'' in which students are placed at the center of an educational journey and arrive at their own understanding of what is being taught.
Holden, Richard, Martinenghi, Fabio I.
openaire   +2 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

The Effect of Explicit Instruction on the Acquisition of Words' Visual Aspects By Second-Grade French-Speaking Children

open access: yesLanguage and Literacy: A Canadian Educational e-journal
This paper explores the most efficient teaching context to learn words’ visual aspects and by second-grade French-speaking children, including those with special needs.
Noémia Ruberto   +3 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

The Effect of Technology-Oriented Differentiated Instruction on Motivation to learn Science

open access: yes, 2023
Integrating technology into teaching approaches has become one of the most effective strategies in teaching development. Therefore, this study aimed to investigate the impact of technology-oriented Differentiated Instruction on thirdgrade students ...
Krishan , Iman Qasim   +1 more
core  

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