Results 101 to 110 of about 485,070 (308)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Enhancing English as a foreign language university students' writing through explicit instruction of conjunctions as cohesive devices: An experimental study. [PDF]

Front Psychol, 2022
Alawerdy AS, Alalwi FS.
europepmc   +1 more source

Japanese pitch accent in an English/Nupe/Hausa trilingual [PDF]

, 2017
Pitch accent, which distinguishes words in Standard Japanese, is difficult for speakers of English to acquire. This is likely to be because pitch in English does not have lexical function.
Muradás-Taylor, Becky
core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

The relative effects of input and output based instruction on the development of L2 knowledge and the relationships with individual differences in working memory

Asian-Pacific Journal of Second and Foreign Language Education
While the relative effects of Processing instruction (PI) and various types of output-based instruction have been widely examined, the types of L2 knowledge generated after receiving instruction are under-researched.
Yan Liang, Lawrence Jun Zhang
doaj   +1 more source

The Essence of Questioning and Explicit Reading Instruction Strategy [PDF]

, 2013
Teacher‟s questioning may function to assist students comprehend more readingmaterials and to enable them to be proficient readers. Yet, the students may beless benefited from which if the teacher neither provides sufficient explicit readingstrategy nor ...
Muzamil, S. (Sa\u27adullah)
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Measuring Explicit Instruction Using Classroom Observations of Student-Teacher Interactions (COSTI). [PDF]

Perspect Behav Sci, 2021
Gunn B, Smolkowski K, Strycker LA, Dennis C.   +3 more
europepmc   +1 more source

Current approaches to orthography instruction for spanish heritage learners: an analysis of intermediate and advanced textbooks [PDF]

, 2015
As it is well known, heritage learners of Spanish have an advantage on oral production and aural comprehension over L2 learners. However, due to their lack of formal instruction in Spanish, their linguistic weaknesses lie on their literacy skills ...
Burgo, Clara
core   +2 more sources

MODEL EXPLICIT INSTRUCTION DALAM PEMBELAJARAN MEMBUAT POSTER

JPPI (Jurnal Pendidikan Islam Pendekatan Interdisipliner), 2021
Abstrak: Penelitian ini bertujuan untuk mengungkapkan efektivitas serta proses penerapan model pembelajaran explicit instruction di kelas VIIIf SMP Negeri 2 Majene dalam pembelajaran poster. Penelitian kuantitatif berjenis eksperimen semu (Quasi Experiment). Desain penelitian  menggunakan pretest-posttest control.
openaire   +1 more source