Results 101 to 110 of about 1,127,197 (289)

The Dramatic Impact of Explicit Instruction on Learning to Read in a New Writing System. [PDF]

Psychol Sci, 2021
Rastle K, Lally C, Davis MH, Taylor JSH.
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Explicit vs. Contrastive-based Instruction of Formulaic Expressions in Developing EFL Learners’ Reading Ability [PDF]

Journal of Applied Linguistics, 2012
As an integrative component of textual structure, formulaic expressions (FEs) play a key role in communicating the message and comprehending the text. Furthermore, interlingually contrastive features of FEs add to their both significance and complexity ...
Gholam-Reza Abbasian, Seyeed Jalil Ehsanian   +1 more
doaj  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Explicit grammar instruction goes nowhere

, 2021
Explicit knowledge of language is defined as conscious knowledge and it is often verbalizable knowledge about language. Implicit knowledge is defined as unconscious knowledge and it is not verbalizable.
Benati, AG
core  

The relative effects of input and output based instruction on the development of L2 knowledge and the relationships with individual differences in working memory

Asian-Pacific Journal of Second and Foreign Language Education
While the relative effects of Processing instruction (PI) and various types of output-based instruction have been widely examined, the types of L2 knowledge generated after receiving instruction are under-researched.
Yan Liang, Lawrence Jun Zhang
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

PENINGKATAN HASIL BELAJAR KOMPETENSI MENGOPERASIKAN APLIKASI PERANGKAT LUNAK DENGAN MENERAPKAN MODEL EXPLICIT INSTRUCTION PADA SISWA KELAS XI PROGRAM KEAHLIAN ADMINISTRASI PERKANTORAN SMK PGRI 2 TAMAN

Economic Education Analysis Journal, 2013
Keberhasilan proses pembelajaran dapat dilihat dari hasil belajar. Dari hasil nilai ulangan harian pada observasi awal di kelas XI AP 3 SMK PGRI 2 Taman Pemalang terdapat 19 siswa belum tuntas belajar dan 25 tuntas belajar dari jumlah 44 siswa.
Abdul Rizal
doaj  

Comparing AI-assisted and teacher-led reading strategy instruction in an EFL context: a quasi-experimental study

Frontiers in Education
Grounded in a metacognitive and distributed-scaffolding framework, this quasi-experimental study examined classroom-level patterns associated with two configurations of reading strategy instruction and with business-as-usual instruction in a university ...
Hesham Aldamen, Mohamad Almashour, Mutasim Al-Deaibes, Rami Alsharefeen   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source