Results 91 to 100 of about 1,127,197 (289)
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Inclusive Design in Assisted Instruction [PDF]
Much instruction starts with abstract representations for which learners have insufficient foundation [1]. The British Standard, BS 7000-6:2005 Guide to Managing Inclusive Design, provides a comprehensive framework that can help all private enterprises ...
Gabriel ZAMFIR
core
Measuring Explicit Instruction Using Classroom Observations of Student-Teacher Interactions (COSTI). [PDF]
Perspect Behav Sci, 2021 Gunn B +3 more
europepmc +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Scaffolding in Assisted Instruction [PDF]
On-The-Job Training, developed as direct instruction, is one of the earliest forms of training. This method is still widely in use today because it requires only a person who knows how to do the task, and the tools the person uses to do the task.
Gabriel ZAMFIR
core
The Enactment of Classroom Justice Through Explicit Instruction: Deciphering the Changes in English as a Foreign Language Teachers' Perceptions and Practices. [PDF]
Front Psychol, 2022 Estaji M, Zhaleh K.
europepmc +1 more source
Explicit apprehensions, implicit instructions: An indirect speech act in~the~grammar
, 2021 Among the languages that grammaticalize the apprehensive domain, some usea subordinator like English lest (‘Don’t run, lest you fall’); others have an apprehensive mood in their verb system (≈ ‘Don’t run, you might fall!’). The Oceaniclanguages of north Vanuatu, whose apprehensional strategies are quite diverse, feature both strategies. This study will
openaire +4 more sources
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Teaching Future School Personnel to Train Parents to Implement Explicit Instruction Interventions. [PDF]
Behav Anal Pract, 2021 Kupzyk S, LaBrot ZC.
europepmc +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source