An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Structural or syntactic priming is a phenomenon in which prior exposure to specific language structures either facilitates or interferes with a learner’s subsequent language production [1].
Rahman Muhammad Asfah, Asfah Indrawaty
doaj +1 more source
The Use of Discourse Completion Task (DCT) as Explicit Instruction on Indonesian Efl Learners' Production of Suggestion Acts [PDF]
There are some activities that can be developed to bring up EFL learners' pragmatic awareness, such as contextualized language practice in given situations, constructed peer dialogues, and metapragmatic discussions. This task-based approach used in these
Aufa, F. (Fauzul)
core
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
A Comparison of Explicit and Implicit Approaches to EAP Teaching to Postgraduate Students
The present study aims to explore the role of explicit and implicit approaches in developing pragmatic competence in postgraduate students as part of the Foreign Language course.
O. A. Boginskaya
doaj +1 more source
'I like it instead of maths' : how pupils with moderate learning difficulties in Scottish primary special schools intuitively solved mathematical word problems [PDF]
This study shows how a group of 24 children in three Scottish primary schools for pupils with moderate learning difficulties responded to word problems following their teachers' introduction to the principles of Cognitively Guided Instruction (CGI).
Moscardini, L.
core +1 more source
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Perbandingan Hasil Belajar Matematika pada Pokok Bahasan Segitiga Melalui Strategi Think-Pair-Square dan Explicit Instruction Siswa Kelas VII SMPN 1 Banyudono Tahun Ajaran 2012/2013 [PDF]
Tujuan penelitian ini adalah untuk mengetahui perbedaan hasil belajar matematika pada pokok bahasan segitiga melalui strategi Think-Pair-Square dan Explicit Instruction. Penelitian ini merupakan penelitian eksperimen. Populasi dalam penelitian ini adalah
, Drs. Ariyanto, M.Pd +1 more
core
DiVM: Model Checking with LLVM and Graph Memory
In this paper, we introduce the concept of a virtual machine with graph-organised memory as a versatile backend for both explicit-state and abstraction-driven verification of software. Our virtual machine uses the LLVM IR as its instruction set, enriched
Barnat, Jiří +3 more
core +1 more source

