Results 61 to 70 of about 1,127,197 (289)

The role of explicit instruction in the acquisition of the present perfect O papel da instrução explícita na aquisição do presente perfect

open access: yesRevista Brasileira de Linguística Aplicada, 2010
This paper aims at analyzing the role of explicit instruction in the learning of the Present Perfect by Brazilian university students in a formal setting.
Ingrid Finger   +1 more
doaj   +1 more source

How to observe the stages of explicit instruction? The "Mirror of Steps of Explicit Instruction" (MSEI) grid, a research and training tool

open access: yes, 2023
This document presents a research and training tool developed as part of a research aimed at a) observing whether teachers who have followed training and coaching increasingly implement a pedagogical approach (explicit instruction) over the course of a school year and b) studying whether these teachers wishing to implement explicit instruction in their
Baco, Christophe   +2 more
openaire   +2 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Integrating form and meaning in L2 pronunciation instruction [PDF]

open access: yes, 2009
One of the central challenges of ESL teaching is striking the right balance between form and meaning. In pronunciation pedagogy, this challenge is compounded because repetitive practice, which has been shown to enhance phonological acquisition and ...
Isaacs, T, Isaacs, Talia
core   +1 more source

A Comparison of Explicit and Implicit Approaches to EAP Teaching to Postgraduate Students

open access: yesВысшее образование в России
The present study aims to explore the role of explicit and implicit approaches in developing pragmatic competence in postgraduate students as part of the Foreign Language course.
O. A. Boginskaya
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Making implicit practice explicit: How do upper secondary teachers describe their reading comprehension strategies instruction? [PDF]

open access: yes, 2014
This study examined the activation of teachers’ tacit knowledge of reading comprehension strategy instruction as part of a teacher professional development course. Although studies have examined professional development courses that inform teachers about
Brevik, Lisbeth M.
core   +1 more source

Some Effects of Explicit Grammar Instruction and Syntactic Priming on Students’ Written Language Production

open access: yesSHS Web of Conferences, 2018
Structural or syntactic priming is a phenomenon in which prior exposure to specific language structures either facilitates or interferes with a learner’s subsequent language production [1].
Rahman Muhammad Asfah, Asfah Indrawaty
doaj   +1 more source

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