Results 51 to 60 of about 485,070 (308)

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi, Daisuke Katagiri, Takeyuki Watadani, Shunichi Matsuda, Hiroshi Kaneko, Noritoshi Arai   +5 more
wiley   +1 more source

Developing reading-writing connections; the impact of explicit instruction of literary devices on the quality of children's narrative writing [PDF]

, 2007
The purpose of this collaborative schools-university study was to investigate how the explicit instruction of literary devices during designated literacy sessions could improve the quality of children's narrative writing. A guiding question for the study
Anderson M., Applebee A., Bakhtin M., Bereiter C., Bershon B., Brown R., Buchanan J., Cairney T., Cairney T., Calkins L., Cochran-Smith M., Crossley-Holland K., Cullinan B., Dyson A. H., Dyson A. H., Flower L., Frater G., Furlong J., Garfeld L., Gates S., Gibbons A., Graham S., Graves D., Graves D., Harris K., Harwayne S., Hayes J. R., Hughes T., Kilworth G., King J., Kress G., Kroll B. M., Lancia P., Leavell A., Lewis M., Lobel A., May H., Maybin J., Merriam S. B., Miles M., Murphy J., Murpurgo M., Murpurgo M., Myhill D., Paramour S., Perera K., Purves A. C., Rosen M., Rosenblatt L. M., Rosenblatt L. M., Short K., Smith J., Thompson E., Tierney R., Vygotsky L. S., Wagner J., Webb N., Wells G., Whittaker R., Wray D.   +59 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Making “academic talk” explicit: Research directions for fostering classroom discourse skills in children from nonmainstream cultures

Schweizerische Zeitschrift für Bildungswissenschaften, 2018
This article focuses on making “school talk,” or classroom discourse, more explicit on two levels. One level involves making explicit for teachers both the nature of school talk, and the reasons why many children may come to school unfamiliar with the ...
Anne x Anne van Kleeck, Amy Louise Schwarz   +1 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Effects of Implicit and Explicit Instruction on Learning Adjective Order

ELT Worldwide: Journal of English Language Teaching, 2022
This study tests the effect of implicit and explicit instruction in the learning of the order of adjectives for advanced second language learners of English. Ten participants were randomly divided into two groups of five each.
Shefali Elizabeth Mathew
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The Impact of Explicit Instruction and Metalinguistic Awareness on Crosslinguistic Interference: Path Framing in Motion Events

Gaziantep Üniversitesi Sosyal Bilimler Dergisi, 2017
The study aimed to investigate the influence of the cross-linguistic variation on the construction of boundarycrossing motion events in the translation production of the Turkish speakers of L2 English and to measure the impact of explicit instruction ...
Abdurrahaman KİLİMCİ
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Assessing the Effectiveness of a Computer Simulation in Introductory Undergraduate Environments [PDF]

, 2006
We present studies documenting the effectiveness of using a computer simulation, specifically the Circuit Construction Kit (CCK) developed as part of the Physics Education Technology Project (PhET) [1, 2], in two environments: an interactive college ...
C. J. Keller, K. K. Perkins, N. D. Finkelstein, S. J. Pollock   +3 more
core   +1 more source