Results 171 to 180 of about 1,736,331 (317)
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Indirect Effect of Maltreatment on Child Cooperation and Exploration Through Maternal Sensitive Guidance. [PDF]
Fam ProcessBoulus JM, Edler K, Valentino K.
europepmc +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Journal of Geochemical Exploration [PDF]
The journal is dedicated to the publication of research studies that cover new developments in the application of analytical geochemistry and geoinformatics.
DINELLI, ENRICO
core
Genetic heterogeneity alleviates behavioral trade-off between exploration and vigilance in <i>Drosophila</i>. [PDF]
iScienceOkuyama T, Sato DX, Takahashi Y.
europepmc +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Mineral Potential of Eastern Pima County, Arizona, by Southwestern Minerals Exploration Association
, 2001 Mineral production is essential to our civilization because minerals provide the raw materials which allow our society to function. Pima County is endowed with many mineral resources, not only copper mines, but also the important products such as sand ...
Southwestern Minerals Exploration Association
core
ST-GICM: A Spatiotemporal Graph Learning Framework with Intrinsic Curiosity for Robust Autonomous Exploration. [PDF]
Sensors (Basel)He L, Liu W, Li W.
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source