Results 61 to 70 of about 2,167,889 (247)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
This research aimed to obtain information on the abundance and natural regeneration population of Calamus zollingeri Beccari and identify dominant trees in the site. The study used the descriptive method with a survey technique.
Titi Kalima, Diana Prameswari
doaj +1 more source
Human activities are increasingly confronting animals with unfamiliar environmental conditions. For example, habitat change and loss often lead to habitat fragmentation, which can create barriers of unsuitable and unfamiliar habitat affecting animal ...
Claudia Mettke-Hofmann +4 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Topographic series with relief shown by hachures.; Sheet title: Palestine Exploration Fund Map.; Title to series on a separate sheet.; Also available in an electronic version via the Internet at: http://nla.gov.au/nla.map-rm1949.Palestine Exploration ...
Palestine Exploration Fund.
core
Identifying Obstacles to Organizational Ambidexterity in Iranian Insurance Industry [PDF]
Objective: Nowadays, organizational ambidexterity is recognized as a solution to increased competition in the market, and its realization requires the simultaneous use of exploration and exploitation. The current research was conducted aiming to identify
Hossein Damghanian +1 more
doaj
Spontaneous object recognition: a promising approach to the comparative study of memory
Spontaneous recognition of a novel object is a popular measure of exploratory behavior, perception and recognition memory in rodent models. Because of its relative simplicity and speed of testing, the variety of stimuli that can be used, and its ...
Rachel eBlaser, Charles eHeyser
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Early signs of pathological cognitive aging in mice lacking high-affinity nicotinic receptors.
In order to address pathological cognitive decline effectively, it is critical to adopt early preventive measures in individuals considered at risk.
Eleni eKonsolaki +4 more
doaj +1 more source

