Results 61 to 70 of about 140,450 (312)
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Mars Science Helicopter Conceptual Design [PDF]
, 2020 Robotic planetary aerial vehicles increase the range of terrain that can be examined, compared to traditional landers and rovers, and have more near-surface capability than orbiters. Aerial mobility is a promising possibility for planetary exploration as
Balaram, Jayarao +15 more
core +1 more source
Subspace Method-based Blind SNR Estimation for Communication between Orbiters in Mars Exploration
ITM Web of Conferences, 2017 In Mars exploration the effective time of communication between orbiters is short, and the relative distance and gesture between them change fast. The signal to noise ratio (SNR) estimation is required in receiver to change adaptively the data rate in ...
Sun Ze-Zhou +2 more
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Strategic Implications of Phobos as a Staging Point for Mars Surface Missions [PDF]
As human exploration endeavors begin to set sights beyond low Earth orbit to the surface of the Moon, exploration of the surface of Mars continues to serve as the horizon destination to help focus development and research efforts.
Drake, Bret G. +2 more
core +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Mars integrated transportation system multistage Mars mission [PDF]
In accordance with the objective of the Mars Integrated Transport System (MITS) program, the Multistage Mars Mission (MSMM) design team developed a profile for a manned mission to Mars.
core +1 more source
Towards an integrated scientific and social case for human space exploration [PDF]
, 2004 I will argue that an ambitious programme of human space exploration, involving a return to the Moon, and eventually human missions to Mars, will add greatly to human knowledge. Gathering such knowledge is the primary aim of science, but science's compart-
Crawford, Ian
core +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
The concept of the Mars airplane was developed as a potential vehicle for unmanned Mars exploration. It is suggested that its most appropriate use would be as an unmanned adjunct to a manned mission.
French, J. R.
core +1 more source