Results 91 to 100 of about 71,949 (309)

Exploring the future of innovation diplomacy

open access: yesEuropean Journal of Futures Research, 2017
Science diplomacy links the two policy domains of foreign affairs and science policy. Competitive thinking and the ways in which this affects global challenges are now putting the globalisation trends in science, technology and innovation under pressure.
Jos Leijten
doaj   +1 more source

Exploring Partnerships for Social Innovation [PDF]

open access: yesSymphonya. Emerging Issues in Management, 2012
Even prior to the recent financial and economic slowdown many enterprises had adopted Corporate Social Responsibility (CSR) strategies to improve their relationships with customers, who are becoming more and more sensible to ethical values. Recently, companies are increasingly promoting social innovation through collaborative initiatives among business,
openaire   +5 more sources

Beyond knowledge brokerage: an exploratory study of innovation intermediaries in an evolving smallholder agricultural system in Kenya [PDF]

open access: yes, 2011
The recognition that innovation occurs in networks of heterogeneous actors and requires broad systemic support beyond knowledge brokering has resulted in a changing landscape of the intermediary domain in an increasingly market-driven agricultural sector
Hall, A.   +3 more
core   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Beyond knowledge brokerage: An exploratory study of innovation intermediaries in an evolving smallholder agricultural system in Kenya [PDF]

open access: yes
The recognition that innovation occurs in networks of heterogeneous actors and requires broad systemic support beyond knowledge brokering has resulted in a changing landscape of the intermediary domain in an increasingly market-driven agricultural sector
Hall, Andy   +3 more
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Public Procurement of Innovation Diffusion: Exploring the Role of Institutions and Institutional Coordination [PDF]

open access: yes
The role of the public agency as a pacer of private sector innovation has been emphasised over the recent years, especially in the context of the EU.
Bakker, Elmer   +2 more
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Understanding Scientific Mobility: Characteristics, Location Decisions, and Knowledge Circulation. A Case Study of Internationally Mobile Austrian Scientists and Researchers [PDF]

open access: yes
In today's knowledge-based global economy, highly qualified people acting as carriers of knowledge are playing a crucial role for the growth and development of organizations, cities and regions.
Kurka, Bernhard   +2 more
core  

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