Results 81 to 90 of about 71,949 (309)
Indonesian Interdisciplinary Journal of Sharia EconomicsThis study examines the influence of leadership characteristics and intellectual resources on organizational performance through innovation ambidexterity mediation in MSMEs in the fashion industry in Bandung.
Sheila Frizqia Jelita, Ruslan Prijadi
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Spin-Off and Innovation in the Pharmaceutical Industry
International Journal of Engineering Business Management, 2014 Parent companies usually undertake corporate spin-offs to cope with higher competitive environments or when, in high technology industries, the differences between R&D investments and intangible assets are larger.
Enzo Peruffo +2 more
doaj +1 more source
Business model innovation for Local Energy Management: a perspective from Swiss utilities
Frontiers in Energy Research, 2016 The successful deployment of the energy transition relies on a deep reorganization of the energy market. Business model innovation is recognized as a key driver of this process.
Emanuele Facchinetti +3 more
doaj +1 more source
Innovation policy; Europe or the member states? [PDF]
Innovation seldom has purely domestic causes and consequences, but how can a European innovation policy complement or substitute national policies? Taking the subsidiarity principle as a starting point, this report discusses the economic rationale of a ...
Albert van der Horst +2 more
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Safe environments for innovation: developing a new multidisciplinary masters programme [PDF]
, 2010 This paper outlines the research and resulting curriculum design activities conducted as a collaborative venture between Northumbria University’s School of Design, School of Computing, Engineering and Information Sciences and Newcastle Business School ...
Bailey, Mark, Smith, Neil
core
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Journal of Innovation & KnowledgeThis study explores how ambidextrous leadership integrates organizational knowledge and innovation to promote business circularity, focusing on the parallel mediating mechanisms of circular exploitative and circular explorative activities.
Noor Ul Hadi
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source