Results 51 to 60 of about 71,949 (309)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Technological activities and their impact on the financial performance of the firm: Exploitation and exploration within and between firms. [PDF]

open access: yes
This article analyzes the financial performance consequences of technology strategies categorized along two dimensions: (1) explorative versus exploitative and (2) solitary versus collaborative.
Belderbos, Rene   +3 more
core   +3 more sources

Breaking Away From Hectic Daily Media Production: Unleashing Explorative Innovation Through Inter-Firm Collaborations

open access: yesMedia and Communication
Beyond the widespread disruption narrative around media innovation, journalism scholarship has put forward valuable remedies to counteract a techno-deterministic perspective by embracing socio-constructivist and socio-technical approaches.
Giordano Zambelli, Luciano Morganti
doaj   +1 more source

Explorative Study of M-Commerce As a Small Business Innovation Strategy

open access: yesIndonesian Journal of Business and Entrepreneurship, 2020
MSMEs have proven to be part of the national economic backbone and have survived the economic crisis that has occurred in Indonesia. However, MSMEs are required to continue to innovate in their business strategies in the rapid disruption of business. The
Idris Idris   +2 more
doaj   +1 more source

Governance and Quintuple Helix innovation model: Insights from the local government of East Luwu Regency, Indonesia

open access: yesFrontiers in Climate, 2022
Climate change issues pose complex social and ecological challenges to rural communities in East Luwu Regency, Indonesia. This can be overcome through a collaborative, sustainable, and distributed innovation process for regional resilience and ...
Abdillah Abdillah   +5 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Analysis of Innovation in Vehicle Industry, With Application of SEM [PDF]

open access: yesمدیریت صنعتی, 2010
Purpose of this paper is development for pattern of a measuring and analysing of innovation in research institutes in vehicle industry. This scale include 3 area: individual innovation, organizational innovation & nature and strength of innovation in ...
Saeid Saeida Ardakani   +3 more
doaj  

Impact of Partial Nephrectomy and Percutaneous Cryoablation on Short-term Health-related Quality of Life—A Prospective Comparative Cohort Study

open access: yesEuropean Urology Open Science, 2022
Background: Partial nephrectomy (PN) is the gold standard for the treatment of stage cT1 renal cell carcinoma (RCC). However, the increasing incidence of RCC in the elderly population calls for alternative minimally invasive treatments to reduce the ...
Theresa Junker   +6 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Leisure and innovation: exploring boundaries [PDF]

open access: yesWorld Leisure Journal, 2019
ABSTRACTInnovation has been widely debated in various fields. However, except for leisure innovation in ageing and digital leisure, scant research has been done on the relationship between leisure ...
Lénia Marques   +1 more
openaire   +1 more source

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