Results 161 to 170 of about 960,650 (292)

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Quantifying Exploratory Behavior In The Human Behavioral Pattern Monitor Using Automated Video Tracking. [PDF]

Meth Psychol
Rosberg H, Miranda A, Holloway BM, Zhang Z, Peek E, Sharp RF, Geyer MA, Young JW, Perry W, Minassian A.   +9 more
europepmc   +1 more source

Chronic Loss of Muscarinic M5 Receptor Function Manifests Disparate Impairments in Exploratory Behavior in Male and Female Mice despite Common Dopamine Regulation. [PDF]

J Neurosci, 2022
Razidlo JA, Fausner SML, Ingebretson AE, Wang LC, Petersen CL, Mirza S, Swank IN, Alvarez VA, Lemos JC.   +8 more
europepmc   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Beyond the burrow: Body condition and sex influence exploratory behavior in desert kangaroo rats (Dipodomys deserti). [PDF]

Biol Open
Moore K, Sadrossadat A, Zhang Z, Huang C, Huynh J, McGowan C, Daley M.   +6 more
europepmc   +1 more source

Whole genome sequence analysis of two subspecies of Companilactobacillus Futsaii and experimental verification of drug resistance and effect on the exploratory behavior of mice based on unique gene. [PDF]

PLoS One, 2022
Xin Z, Wei X, Jiao Q, Gou Q, Zhang Y, Peng C, Pan Q.   +6 more
europepmc   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Assessment of the associative determinants of tolerance to the effects of cannabis extract on exploratory behavior in rats. [PDF]

Drug Alcohol Depend Rep
Varas FI, Miguez G, Quezada-Scholz VE, Ibáñez-Jiménez E, Aguilar C, Ramírez S, Badilla J, Alfaro F, Bertin F, Bustamante J, Angulo R, Fuentealba JA, Vergés A, Laborda MA.   +13 more
europepmc   +1 more source

Infection with intestinal helminth (Hymenolepis diminuta) impacts exploratory behavior and cognitive processes in rats by changing the central level of neurotransmitters. [PDF]

PLoS Pathog, 2022
Blecharz-Klin K, Świerczyńska M, Piechal A, Wawer A, Joniec-Maciejak I, Pyrzanowska J, Wojnar E, Zawistowska-Deniziak A, Sulima-Celińska A, Młocicki D, Mirowska-Guzel D.   +10 more
europepmc   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source