Results 151 to 160 of about 25,538,498 (274)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Psychometric Assessment of a New Pain-Specific Patient-Reported Outcome Measure for Pelvic Floor Surgery Using Exploratory Factor Analysis. [PDF]

Int Urogynecol J
Hoque SS, Ahern S, O'Connell HE, Ruseckaite R.   +3 more
europepmc   +1 more source

How many categories are there in crossmodal correspondences? A study based on exploratory factor analysis. [PDF]

PLoS One, 2023
Ohtake Y, Tanaka K, Yamamoto K.
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Body composition and cognitive function in Chinese rural adults: an exploratory factor analysis and network analysis. [PDF]

Front Aging Neurosci
Wang L, Liu H, Meng X, Tuo Z, Zhou Y, Wu P, Wang E, Shen Y, Wang Z, Deng C, Liu Y, Tang Y, Zhou Y.   +12 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

The workplace expectations and preferences of Gen Z nurses: exploratory factor analysis. [PDF]

BMC Nurs
Al-Moteri M, Althobaiti E, Aljuaid GM, Alotaibe MF, Alharthi RA, Aljuaid MA, Alboqami SF, Aljuaid J, Berdida DJE, Grande RAN, Saleh MSM, Algamdi MM, Alalyani M, Alrehaili AA.   +13 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Exploratory Factor Analysis of the Adversity Appraisal Questionnaire (AAQ). [PDF]

J Psychopathol Behav Assess
Lee JJ, Lowenthal G, Jackson Y.
europepmc   +1 more source

Exploratory Factor Analysis of a Computerized Case-Based F-Type Testlet Variant. [PDF]

Med Sci Educ, 2023
Kıyak YS, Budakoğlu Iİ, Bakan Kalaycıoğlu D, Coşkun Ö.   +3 more
europepmc   +1 more source