Results 51 to 60 of about 4,364,005 (268)

DEVELOPMENT AND PSYCHOMETRIC PROPERTIES OF ADVERSE CHILDHOOD EXPERIENCES SCALE FOR ADOLESCENTS

open access: yesPakistan Armed Forces Medical Journal, 2020
Objective: To develop a scale and establish psychometric properties to measure Adverse Childhood Experiences of Adolescents in Urdu language. Study Design: Cross sectional analytical study.
Maryam Riaz, Zaqia Bano
doaj  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

DEVELOPING ITEMS FOR MEASURING QUALITY OF WORK LIFE AMONG MALAYSIAN ACADEMICS: AN EXPLORATORY FACTOR ANALYSIS PROCEDURE

open access: yesHumanities & Social Sciences Reviews, 2020
Purpose of the study: Quality of work life (QWL) is vital for all establishments to continue to hire and retain high-performance workers. However, from the review of previous literature on QWL, little is known about the dimensions that constitute high ...
Amauche Ehido   +3 more
semanticscholar   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

What Influences Tourist’ Visit Decision to Coastal Area? A Lesson Learned from Southern Beaches of West Java

open access: yesAsian Journal of Technology Management, 2020
. Indonesia, as an archipelago country, posits the third rank of the world’s longest coastline list. The potential of coastal tourism was voluminous to be developed in the future. Since the tourism contribution has a positive inclination during the years
Kyoichi Kijima   +4 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Pengembangan dan Validasi Instrumen Pengukuran Efektivitas Tim di Usaha Mikro Kecil dan Menengah (UMKM)

open access: yesPsikohumaniora: Jurnal Penelitian Psikologi, 2018
In general, research on the development of teamwork-measuring instru­ments is associated with the corporate context. While in Indonesia, research in the context of small and medium enterprises is equally important.
Faradilla Iedliany   +2 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Psychometric properties of the Persian version of Brief Scale of Unsafe Behaviors of Motorcyclists referred to the Persian Gulf clearance headquarters

open access: yesPayesh, 2019
Objective (s): Motorcyclists are vulnerable to traffic accidents. The purpose of this research was to evaluate the psychometric properties of the Persian version of Brief Scale of Unsafe Behaviors of motorcyclists.
Nasim Narimani   +2 more
doaj  

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