Results 71 to 80 of about 335,881 (245)

Development and validation of a questionnaire to measure a medical student's interest in the subject of community medicine

Indian Journal of Community Medicine
Background: Lack of interest has been cited by many studies as the predominant cause for students undervaluing the subject of Community Medicine. However, there are few valid and reliable tools that could measure this interest.
Syed I Ali, Jarina Begum, Abhishek Kumar, Swati Shikha, Sachin K Patil, Ratnesh Sinha   +5 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Identifying of effective factors on job dissatisfaction of primary school teachers in Bojnord city (Factor Analysis research)

Salāmat-i kār-i Īrān, 2017
Background and aims: Feel job satisfaction is the most basic components of mental health and an important factor in career success. The aim of this study was identify of effective factors on job dissatisfaction of primary school teachers of Bojnord city.
Tayebe Rahimi Pordanjani, Ali Mohamadzade Ebrahimi   +1 more
doaj  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Analysis of Cybersecurity Awareness Among Social Media Users Among Teenagers Using Exploratory Factor Analysis (EFA) & Confirmatory Factor Analysis (CFA) Methods

Journal of Electrical Engineering and Computer
Nowadays, security awareness is very important for social media users, especially teenagers. Many users become victims of cybercrime due to the lack of education about cybersecurity awareness.
Sofia Angela, Muhamat Maariful Huda, Rizqi Darma Rusdiyan   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Development of a quantitative model for performance assessment of urban green buildings: exploratory and confirmatory factor analysis

سلامت و محیط, 2022
Background and Objective: This study aims to develop a quantitative model for the performance evaluation of urban green buildings using exploratory and confirmatory factor analysis.
Hedieh Chorom, Nabiollah Mansouri, Mohammad Hassan Behzadi   +2 more
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, Volume 20, Issue 6, Page 1494-1512, June 2026.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Factors that May Lead on the Non-renewal of Certified Organic Product According to Organic Producers in Brazil

Revista de Economia e Sociologia Rural
: The regulatory process of the organic sector in Brazil began in 1999 and has gone through several changes, culminating in the Decree-Law of December 2007, which established rules for the production and trading of organic products in Brazil.
Andréa Rossi Scalco, Sandra Cristina de Oliveira, Giuliana Santini Pigatto, Juliana Cobre   +3 more
doaj   +1 more source