Results 51 to 60 of about 25,538,498 (274)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Establishing construct validity for a department perception inventory : utilizing exploratory factor analysis with small samples

open access: yes, 2020
Exploratory factor analysis (EFA) is often used in the scale development process to determine the existence of latent factors and establish construct validity.
Nguyen, Michael (Student at Ball State University)
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Validation of a Child Abuse Questionnaire in Iranian Children with Exploratory and Confirmatory Factor Analysis

open access: yesCaspian Journal of Health Research, 2016
Objectives: Protecting children from abuse is a public responsibility. Having a valid tool to assess child abuse is necessary.  Methods: The present analysis variance–covariance matrix study recruited 360 elementary school students ...
Hashem Mohammadian   +2 more
doaj  

The creation and validation of the Measure of Effective Attributes of Trainers (MEAT)

open access: yesImplementation Science, 2017
Background Training is a core component in the implementation of empirically supported treatments, especially in the case of psychosocial interventions targeting mental illness.
Meredith R. Boyd   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

An exploratory factor analysis and reliability analysis for green affordable housing criteria instrument [PDF]

open access: yes, 2017
A Green Affordable Housing (GAH) criteria questionnaire was developed to determine stakeholders’ preferences and their willingness to pay according to GAH criteria and features in Malaysia.
Zulkepli, Masitah   +2 more
core   +1 more source

Exploratory factor analysis (N = 422).

open access: yes, 2021
Exploratory factor analysis (N = 422).
Tunvir Ahamed Shohel (10720100)   +7 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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