Results 81 to 90 of about 341,973 (244)

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Factors that May Lead on the Non-renewal of Certified Organic Product According to Organic Producers in Brazil

Revista de Economia e Sociologia Rural
: The regulatory process of the organic sector in Brazil began in 1999 and has gone through several changes, culminating in the Decree-Law of December 2007, which established rules for the production and trading of organic products in Brazil.
Andréa Rossi Scalco, Sandra Cristina de Oliveira, Giuliana Santini Pigatto, Juliana Cobre   +3 more
doaj   +1 more source

Development of a quantitative model for performance assessment of urban green buildings: exploratory and confirmatory factor analysis

سلامت و محیط, 2022
Background and Objective: This study aims to develop a quantitative model for the performance evaluation of urban green buildings using exploratory and confirmatory factor analysis.
Hedieh Chorom, Nabiollah Mansouri, Mohammad Hassan Behzadi   +2 more
doaj  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Practices and Challenges of the Validity of Exploratory Factor Analysis (EFA)-Based Assessment Instruments: A Systematic Literature Review 2020–2025

Edukasia
The validity of assessment instruments is the basis for ensuring the quality of learning assessment. A valid instrument allows the results of the evaluation to be used appropriately in educational decision-making. This study aims to examine the practice
Abd Mannan, Suparto Suparto, Kusaeri Kusaeri   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Psychometric properties of the American version of the Chronic Uncertainty scale: long and short version (CU-40; CU-20)

BMC Psychology
Background Uncertainty is a widespread phenomenon experienced worldwide. The bulk of existing research to date has focused on transitory or acute experiences of uncertainty, often in the particular context of illness.
Shiwa Ghassabei, Walid A. Afifi, Tamara Afifi, Katja Petrowski   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source