Results 81 to 90 of about 1,657,010 (361)

Functional variation among LPMOs revealed by the inhibitory effects of cyanide and buffer ions

FEBS Letters, Volume 599, Issue 9, Page 1317-1336, May 2025.
This study addresses the inhibition of lytic polysaccharide monooxygenases (LPMOs) by cyanide and explains how and why the magnitude of observed inhibitory effects depends on the way LPMO reactions are setup and on the type of LPMO. Enzymes known as lytic polysaccharide monooxygenases (LPMOs) are mono‐copper polysaccharide‐degrading peroxygenases that ...
Ole Golten, Lorenz Schwaiger, Zarah Forsberg, Kelsi R. Hall, Anton A. Stepnov, Tom Z. Emrich‐Mills, Iván Ayuso‐Fernández, Morten Sørlie, Roland Ludwig, Åsmund Kjendseth Røhr, Vincent G. H. Eijsink   +10 more
wiley   +1 more source

Associations between physical multimorbidity patterns and common mental health disorders in middle-aged adults: A prospective analysis using data from the UK Biobank

The Lancet Regional Health. Europe, 2021
Background: We aimed to identify specific patterns of physical multimorbidity, defined as the presence of two or more physical long-term conditions, and to examine the extent to which these specific patterns could predict future incident and persistent ...
Amy Ronaldson, Jorge Arias de la Torre, Matthew Prina, David Armstrong, Jayati Das-Munshi, Stephani Hatch, Rob Stewart, Matthew Hotopf, Alexandru Dregan   +8 more
doaj  

Interpersonal and affective dimensions of psychopathic traits in adolescents : development and validation of a self-report instrument [PDF]

, 2013
We report the development and psychometric evaluations of a self-report instrument designed to screen for psychopathic traits among mainstream community adolescents. Tests of item functioning were initially conducted with 26 adolescents.
A Raine, AE Forth, AE Forth, AL Glenn, American Psychiatric Association, Australian Bureau of Statistics, BM Byrne, BR Loney, C Neumann, C Sharp, Carol Tan, CJ Patrick, CS Neumann, D Seagrave, DA Pardini, DA Pardini, DC Murrie, DJ Cooke, DJ Cooke, DR Lynam, DR Lynam, DR Lynam, DR Lynam, DR Lynam, DS Kosson, EG Carmines, F Declercq, FJ Floyd, GM Vincent, H Andershed, H Andershed, HF Kaiser, HF Kaiser, J Asscher, J Vitale, JE Lochman, JF Edens, JF Edens, JF Hair Jr, JL Horn, JS Kotler, K Nijhof, K Sevecke, L Guttman, L Johnstone, LA Baker, MA Campbell, MA Marsee, MC Dolan, MG Vaughn, Microsoft Corporation, MJ Vitacco, MJ Vitacco, MR Dadds, MS Bartlett, P Chauhan, P Kline, PJ Frick, PJ Frick, PJ Frick, PJ Frick, PJ Frick, R Flesch, R Goodman, RB Cattell, RD Hare, RD Hare, RD Hare, RD Hare, RD Hare, RJR Blair, RT Salekin, RT Salekin, RT Salekin, S Benning, S Houghton, SBG Eysenck, SE Spain, SF White, Simon C. Hunter, SO Lilienfeld, SO Lilienfeld, SR Penney, Stephen Houghton, T Millon, TD Barry, TD Barry, TE Moffitt, Umneea Khan, Y Baardewijk van   +89 more
core   +1 more source

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

FEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung, Mikhail G. Dozmorov, SuJeong Song, Theingi Aung, Min Hee Park, Patricia J. Sime, Wook‐Jin Chae   +6 more
wiley   +1 more source

Pengembangan dan Validasi Instrumen Pengukuran Efektivitas Tim di Usaha Mikro Kecil dan Menengah (UMKM)

Psikohumaniora: Jurnal Penelitian Psikologi, 2018
In general, research on the development of teamwork-measuring instru­ments is associated with the corporate context. While in Indonesia, research in the context of small and medium enterprises is equally important.
Faradilla Iedliany, Arief Fahmie, Elisa Kusrini   +2 more
doaj   +1 more source

A Comparative Usability Study of Two-Factor Authentication [PDF]

, 2014
Two-factor authentication (2F) aims to enhance resilience of password-based authentication by requiring users to provide an additional authentication factor, e.g., a code generated by a security token. However, it also introduces non-negligible costs for
De Cristofaro, Emiliano, Du, Honglu, Freudiger, Julien, Norcie, Greg   +3 more
core   +1 more source

Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases

FEBS Letters, Volume 599, Issue 8, Page 1094-1112, April 2025.
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher, Paula Armina V. Buco, Jia Q. Truong, Paul A. Ramsland, Monique F. Smeets, Carl R. Walkley, Jessica K. Holien   +6 more
wiley   +1 more source

Factors influencing to use of Bluezone [PDF]

arXiv, 2023
This study aims to understand the main factors and their influence on the behavioral intention of users about using Bluezone. Surveys are sent to users through the Google Form tool. Experimental results through analysis of exploratory factors on 224 survey subjects show that there are 4 main factors affecting user behavior. Structural equation modeling
arxiv  

The apo LETM1 F‐EF‐hand adopts a closed conformation that underlies a multi‐modal sensory role in mitochondria

FEBS Letters, Volume 599, Issue 7, Page 971-988, April 2025.
We present the first solution structure of the Ca2+‐depleted LETM1 F‐EF‐hand through a D676A/N678A Ca2+ binding‐deficient mutant, revealing a closed hydrophobic cleft caused by a unique F1‐helix pivot. The apo LETM1 F‐EF‐hand exhibits regiospecific hot and cold unfolding, sensitivity to physiological pH changes and potential for promiscuous heterotypic
Qi‐Tong Lin, Danielle M. Colussi, Peter B. Stathopulos   +2 more
wiley   +1 more source

Psychometric properties of the Persian version of Brief Scale of Unsafe Behaviors of Motorcyclists referred to the Persian Gulf clearance headquarters

Payesh, 2019
Objective (s): Motorcyclists are vulnerable to traffic accidents. The purpose of this research was to evaluate the psychometric properties of the Persian version of Brief Scale of Unsafe Behaviors of motorcyclists.
Nasim Narimani, Hashem Mohamadian, Sharareh Rostamniakan   +2 more
doaj