Continued post-weaning social isolation is associated with persistent, sex-specific changes in sociability and social interaction dynamics in mice. [PDF]
Yamamuro K +9 more
europepmc +1 more source
A Thickness‐Invariant Origami Robot With Integrated Actuation and Multimodal Locomotion
A thickness‐invariant variation on the Yoshimura origami pattern is used as the basis of a robot, allowing power, actuation, and control systems to be embedded within the thickened panels of the pattern. The robot uses multiple kinematic branches to achieve distinct modes of locomotion, such as walking, running, galloping, and turning. ABSTRACT Origami
Davis Wing +4 more
wiley +1 more source
Crossing the comfort zone: rabbit appeasing pheromone enhances acclimation to a novel environment. [PDF]
Agan UB +5 more
europepmc +1 more source
Two‐photon calcium imaging in behaving 5xFAD mice reveals early CA1 coding deficits before behavioral decline. Task‐related place cell activity and splitter cell trajectory coding are impaired, with reduced retrospective dominance and greater prospective weighting.
Yimei Li +8 more
wiley +1 more source
Dihydromyricetin Is Associated with Healthspan-Related Phenotypes and Neuroprotection in <i>Caenorhabditis elegans</i>, Alongside Redox and Mitochondrial Quality-Control Changes. [PDF]
Jo YH, Cho H, Lee DS, Cho JH.
europepmc +1 more source
As a novel adipose‐derived neurotrophic factor, Follistatin‐like 1 is endocytosed by sympathetic neurons primarily via tropomyosin‐related kinase B. This process promotes sympathetic innervation in adipose tissue and norepinephrine release, leading to white adipose tissue browning, enhanced thermogenesis, and anti‐obesity effects in mice.
Xiao‐Wei Jia +13 more
wiley +1 more source
Direct Comparison of Two Commonly Used Prenatal Valproate Doses Identifies Different Sex- and Age-Related Neurobehavioral Outcomes Across Development. [PDF]
Becker M +6 more
europepmc +1 more source
This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Yingdong Liu +23 more
wiley +1 more source
Continuous OFT-Based Behavioral Phenotyping Reveals Neural Stem Cell-Associated Shifts in Depression-like Mice. [PDF]
Wang H +7 more
europepmc +1 more source
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu +5 more
wiley +1 more source

