Results 61 to 70 of about 176,958 (272)

Assessing Model Fit: Caveats and Recommendations for Confirmatory Factor Analysis and Exploratory Structural Equation Modeling [PDF]

open access: yesMeasurement in Physical Education and Exercise Science, 2015
Despite the limitations of overgeneralizing cutoff values for confirmatory factor analysis (CFA; e.g., Marsh, Hau, & Wen, 2004), they are still often employed as golden rules for assessing factorial validity in sport and exercise psychology. The purpose of this study was to investigate the appropriateness of using the CFA approach with these cutoff ...
Nicholls, Adam R.   +3 more
openaire   +4 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Analysis of corporate environmental reports using statistical techniques and data mining [PDF]

open access: yes, 2009
Measuring the effectiveness of corporate environmental reports, it being highly qualitative and less regulated, is often considered as a daunting task. The task becomes more complex if comparisons are to be performed. This study is undertaken to overcome
Issac, Biju, Modapothala, Jashua Rajesh
core  

Validity evidence of the organizational justice scale in Spain [PDF]

open access: yes, 2018
Resumen tomado de la publicaciónEvidencias de validez de la Escala de Justicia Organizacional en España. Antecedentes: el interés por la medición de la percepción de justicia organizacional ha aumentado en los últimos años debido a su demostrada relación
Castaño Pérez, Ana María   +1 more
core   +1 more source

Rationale and Applicability of Exploratory Structural Equation Modeling (ESEM) in psychoeducational contexts

open access: yesPsicothema, 2017
In last few years, the use of confirmatory factor analysis (CFA) has become dominant in structural validation of psychological tests. However, the requirement of latent variables only loading on specific target items introduces some constraints on the solutions found, namely a factor solution that links some items only in one specific dimension.
Gomes, Cristiano Mauro Assis   +2 more
openaire   +5 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Dimensions of perceived product quality – understanding the consumer’s view [PDF]

open access: yes, 2009
Objectives. We identify core product quality components from the consumers’ perspective and construct a psychometrically sound instrument for their assessment within different purchasing contexts. Methods.
Brändli, Dieter   +3 more
core   +1 more source

A new look at the big five factor structure through exploratory structural equation modeling.

open access: yesPsychological Assessment, 2010
NEO instruments are widely used to assess Big Five personality factors, but confirmatory factor analyses (CFAs) conducted at the item level do not support their a priori structure due, in part, to the overly restrictive CFA assumptions. We demonstrate that exploratory structural equation modeling (ESEM), an integration of CFA and exploratory factor ...
Herbert W. Marsh   +6 more
openaire   +6 more sources

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

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