Results 91 to 100 of about 5,007,763 (313)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Second land utilization survey of Britain [cartographic material] : index to 1:25,000 series.

open access: yes, 1964
"The sheet lines of a standard sheet are 20 Kms. x Kms. with exceptions for some coastal sheets."; "These maps depicts 64 categories of land use, overprinted in eleven colours on 1:25,000 Ordnance Survey base maps.
Great Britain. Ordnance Survey.
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

2008 AdvanceVT Work/Life Survey Questionnaire

open access: yes, 2008
This survey is being administered in order to help improve the climate for faculty members at Virginia Tech. Aggregate data from the survey will be shared with deans, department heads, and others in order to promote discussion about strategies to help ...
Virginia Tech. Center for Survey Research
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Musgrave, South Australia [cartographic material].

open access: yes, 1941
1st ed. Relief shown by hachures, form lines and spot heights.; "This map is compiled from the latest Commonwealth and State information and is not the result of precise military survey"; "Printed by A.H.Q.
Australia. Army. Survey Corps.
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

[Plane table survey maps of Meredith, Geelong and Portarlington regions, Victoria]. C [cartographic material] /

open access: yes, 1914
Manuscript plane table survey map of Meredith, Geelong and Portarlington regions, Victoria. Relief shown by contours and spot heights.; Title supplied by cataloguer.; Also available in an electronic version via the Internet at: http://nla.gov.au/nla.map ...
Australia. Army. Survey Corps.
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Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Coober Pedy, South Australia [cartographic material].

open access: yes, 1942
1st ed. Shows telephone and power lines, electric power stations, roads, railways and aerodromes.; Relief shown by hachures, form lines and spot heights.; "This map is compiled from the latest Commonwealth and State information and is not the result of ...
Australia. Army. Survey Corps.
core  

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