Results 101 to 110 of about 940,336 (300)

The Next Generation Deep Extragalactic Exploratory Public (NGDEEP) Survey

The Astrophysical Journal Letters
We present the Next Generation Deep Extragalactic Exploratory Public (NGDEEP) Survey, a deep slitless spectroscopic and imaging Cycle 1 JWST treasury survey designed to constrain feedback mechanisms in low-mass galaxies across cosmic time. NGDEEP targets
Micaela B. Bagley, Nor Pirzkal, Steven L. Finkelstein, Casey Papovich, Danielle A. Berg, Jennifer M. Lotz, Gene C. K. Leung, Henry C. Ferguson, Anton M. Koekemoer, Mark Dickinson, Jeyhan S. Kartaltepe, Dale D. Kocevski, Rachel S. Somerville, L. Y. Aaron Yung, Bren E. Backhaus, Caitlin M. Casey, Marco Castellano, Óscar A. Chávez Ortiz, Katherine Chworowsky, Isabella G. Cox, Romeel Davé, Kelcey Davis, Vicente Estrada-Carpenter, Adriano Fontana, Seiji Fujimoto, Jonathan P. Gardner, Mauro Giavalisco, Andrea Grazian, Norman A. Grogin, Nimish P. Hathi, Taylor A. Hutchison, Anne E. Jaskot, Intae Jung, Lisa J. Kewley, Allison Kirkpatrick, Rebecca L. Larson, Jasleen Matharu, Priyamvada Natarajan, Laura Pentericci, Pablo G. Pérez-González, Swara Ravindranath, Barry Rothberg, Russell Ryan, Lu Shen, Raymond C. Simons, Gregory F. Snyder, Jonathan R. Trump, Stephen M. Wilkins   +47 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Quality management and cost of education at private universities in Bangladesh: An evaluation [PDF]

, 2007
An exploratory survey was conducted to analyze the consumers’ evaluation of private higher education sectors in Bangladesh with particular reference to the quality as well as the cost of education.
A. Ashraf, Mohammad
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Socialisation, community, and shopping malls : an empirical study at Auckland's St. Lukes Mall : examining the role the mall plays for its patrons : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Social Anthropology at Massey University [PDF]

, 1996
With the steady growth in the number of shopping malls being constructed, and the high level of media attention they have been receiving, this exploratory study investigated the role shopping centres play for their patrons and conceptualized the findings
Farmer, Nathan Jerome
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Why do Chinese multinationals in South Africa get benefits from digital business strategy?

South African Journal of Economic and Management Sciences
Background: Chinese multinational enterprises (MNEs) are obsessed with implementing digital business strategy in global competition, but there is limited knowledge about how and when the MNEs can achieve performance.
Kuizhen Rong, Ruhong Liu
doaj   +1 more source

Cultural Identity of Labor and Delivery Nurses In the Assessment of Pregnant Patients For Interpersonal Violence [PDF]

, 2006
Objective: Identification of barriers to assessment of interpersonal violence (IPV) in pregnant women. Design: An exploratory descriptive study Setting: The labor and delivery department of a public county hospital Participants: 34 nurses, representing 8
Smith, Ramona Nichols
core   +1 more source