Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li +4 more
wiley +1 more source
A pipeline leakage detection method for boiler energy operation system using enhanced SVM-based acoustic emission technology. [PDF]
Yuan T, Zhang X, Zhang Q, Tan M.
europepmc +1 more source
Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing +10 more
wiley +1 more source
Scenario analysis of HAZMAT transportation road traffic crashs on China's highways based on AcciNet-RFs. [PDF]
Dai Z, Fan R, Meng W, Chen Y, Tian S.
europepmc +1 more source
Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong +12 more
wiley +1 more source
Beyond diagonal noise: A better predator-prey modeling framework with cross-covariance. [PDF]
Yu J, Wang LS.
europepmc +1 more source
Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing
Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley +1 more source
Study on Regional Evolution Characteristics of Coal Spontaneous Combustion and Gas Coupling Disaster in Composite Goaf with No-Pillar Mining. [PDF]
Kong D +5 more
europepmc +1 more source
The TPR‐LYTACs nanomaterial offers a dual‐pathway strategy for precise gouty arthritis treatment by targeting and degrading the ROS‐producing enzyme NOX2 inside macrophages while its antioxidant core clears accumulated ROS outside. This “source inhibition and microenvironment scavenging” approach, guided by NIR‐II imaging, effectively controls local ...
Jian Zhang +15 more
wiley +1 more source
Objective Longitudinal Monitoring of Burn Wound Area Using 3D Surface Scanning: A Pilot Study. [PDF]
Ondrejová B +6 more
europepmc +1 more source

