Results 61 to 70 of about 260,518 (341)

Longevity and pleural mesothelioma: age-period-cohort analysis of incidence data from the Surveillance, Epidemiology, and End Results (SEER) Program, 1973–2013

open access: yesBMC Research Notes, 2018
Objective This study investigates the hypothesis that an increasing fraction of incident pleural mesothelioma (PM) in the US population may be related to longevity, i.e., to expansion of the population over age 75 years with an age-related elevation in ...
Brent D. Kerger
doaj   +1 more source

Revision arthroplasty after unicompartimental knee arthroplasty

open access: yesJournal of Orthopaedic Surgery and Research, 2021
Background Unicompartimental knee arthroplasty (UKA) is a promising and increasing application to treat unicompartimental knee osteoarthritis. However, revision arthroplasty numbers after UKA are unknown. Therefore, aim of this study was to determine the
Nike Walter   +6 more
doaj   +1 more source

A new theoretical interpretation of Archie’s saturation exponent

open access: yes, 2017
. This paper describes the extension of the concepts of connectedness and conservation of connectedness that underlie the generalized Archie's law for n phases to the interpretation of the saturation exponent.
P. Glover
semanticscholar   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

100 % Fruit juice and measures of glucose control and insulin sensitivity: a systematic review and meta-analysis of randomised controlled trials

open access: yesJournal of Nutritional Science, 2017
Studies on the effects of consuming 100 % fruit juice on measures of glycaemic control are conflicting. The purpose of the present study was to systematically review and quantitatively summarise results from randomised controlled trials (RCT) examining ...
Mary M. Murphy   +3 more
doaj   +1 more source

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

Simplified Successive Cancellation Decoding of Polar Codes With Medium-Dimensional Binary Kernels

open access: yesIEEE Access, 2018
A method is proposed, called l-formula, to design efficient successive cancellation (SC) decoding of polar codes with medium-dimensional binary kernels (dimensions up to 16).
Zhiliang Huang   +5 more
doaj   +1 more source

Critical crack path assessments in failure investigations [PDF]

open access: yesFracture and Structural Integrity, 2015
This paper presents a case study in which identification of the controlling crack path was critical to identifying the root cause of the failure. The case involves the rupture of a 30-inch (0.76 m) natural gas pipeline in 2010 that tragically led to ...
Robert D. Caligiuri
doaj   +1 more source

Quantified exponence constraints and the typology of exponence

open access: yesProceedings of the Annual Meetings on Phonology, 2018
Both phonologically conditioned suppletive allomorphy (PCSA) and multiple exponence (ME) involve one-to-many mapping between morphosyntactic information and phonological representations. Though they are usually viewed as separate phenomena, the plural marking of Lower Jubba Maay exhibits properties of both PCSA and ME, indicating that they are ...
openaire   +2 more sources

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy