Results 61 to 70 of about 625,164 (340)
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Dynamical Critical Exponent for Two-Species Totally Asymmetric Diffusion on a Ring [PDF]
, 2010 We present a study of the two species totally asymmetric diffusion model using the Bethe ansatz. The Hamiltonian has $U_q(SU(3))$ symmetry. We derive the nested Bethe ansatz equations and obtain the dynamical critical exponent from the finite-size ...
Wehefritz-Kaufmann, Birgit
core +2 more sources
FEBS Open Bio, EarlyView.Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr +5 more
wiley +1 more source
Evaluation of Fire Spread and Suppression Techniques in Micro-Mobility Battery Packs
ECS AdvancesLithium-ion battery packs used in micro-mobility devices, such as e-bikes and e-scooters can lead to substantial safety hazards should a single cell go into thermal runaway.
Daniel A. Torelli +4 more
doaj +1 more source
Critical crack path assessments in failure investigations [PDF]
Fracture and Structural Integrity, 2015 This paper presents a case study in which identification of the controlling crack path was critical to identifying the root cause of the failure. The case involves the rupture of a 30-inch (0.76 m) natural gas pipeline in 2010 that tragically led to ...
Robert D. Caligiuri
doaj +1 more source
Interplay between RNA‐protein interactions and RNA structures in gene regulation
FEBS Open Bio, EarlyView.Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
Industry R&D needs in hydrogen safety
Applications in Energy and Combustion ScienceHydrogen's unique physicochemical and combustion properties make it stand out among fuels as new hydrogen production technologies, means of transportation, and consumers emerge.
Harri Kytömaa +6 more
doaj +1 more source
Critical exponents of the driven elastic string in a disordered medium
, 2005 We analyze the harmonic elastic string driven through a continuous random potential above the depinning threshold. The velocity exponent beta = 0.33(2) is calculated.
H. Gao +4 more
core +1 more source
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source
Obesity PillarsBackground: The fixed-dose extended-release combination of naltrexone/bupropion (NB-ER) is indicated to treat overweight and obesity in adults as an adjunct to a reduced-calorie diet and increased physical activity.
Michael Kyle +13 more
doaj +1 more source