Results 61 to 70 of about 824,647 (276)

Probabilistic Fragmentation and Effective Power Law

open access: yes, 1996
A simple fragmentation model is introduced and analysed. We show that, under very general conditions, an effective power law for the mass distribution arises with realistic exponent.
A. Hadas   +8 more
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Expurgation Exponent of Leaked Information in Privacy Amplification for Binary Sources

open access: yes, 2012
We investigate the privacy amplification problem in which Eve can observe the uniform binary source through a binary erasure channel (BEC) or a binary symmetric channel (BSC).
Watanabe, Shun
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Critical crack path assessments in failure investigations [PDF]

open access: yesFracture and Structural Integrity, 2015
This paper presents a case study in which identification of the controlling crack path was critical to identifying the root cause of the failure. The case involves the rupture of a 30-inch (0.76 m) natural gas pipeline in 2010 that tragically led to ...
Robert D. Caligiuri
doaj   +1 more source

Allometric Exponent and Randomness

open access: yes, 2013
An allometric height-mass exponent $\gamma$ gives an approximative power-law relation $ \propto H^\gamma$ between the average mass $$ and the height $H$, for a sample of individuals.
Kim, Beom Jun   +2 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

A new theoretical interpretation of Archie’s saturation exponent

open access: yes, 2017
. This paper describes the extension of the concepts of connectedness and conservation of connectedness that underlie the generalized Archie's law for n phases to the interpretation of the saturation exponent.
P. Glover
semanticscholar   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Evaluation of Fire Spread and Suppression Techniques in Micro-Mobility Battery Packs

open access: yesECS Advances
Lithium-ion battery packs used in micro-mobility devices, such as e-bikes and e-scooters can lead to substantial safety hazards should a single cell go into thermal runaway.
Daniel A. Torelli   +4 more
doaj   +1 more source

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