Results 71 to 80 of about 117,020 (320)

Small perturbations may change the sign of Lyapunov exponents for linear SDEs [PDF]

arXiv, 2022
In this paper, we study the existence of $n$-dimensional linear stochastic differential equations (SDEs) such that the sign of Lyapunov exponents is changed under an exponentially decaying perturbation. First, we show that the equation with all positive Lyapunov exponents will have $n-1$ linearly independent solutions with negative Lyapunov exponents ...
arxiv  

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, EarlyView.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

Molecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen, Pieter‐Jan Volders, Ellen Geerdens, Severine Berden, Joni Van der Meulen, Aaron De Cock, Stefanie Vermeire, Jacques Van Huysse, Marie de Barsy, Gabriela Beniuga, Wendy W. J. de Leng, Anne M. L. Jansen, Imke Demers, Zeliha Ozgur, Hendrikus Jan Dubbink, Ernst‐Jan M. Speel, Wilfred F. J. van IJcken, Brigitte Maes   +17 more
wiley   +1 more source

The homomorphism domination exponent

European Journal of Combinatorics, 2011
23 ...
Benjamin Rossman, Swastik Kopparty
openaire   +3 more sources

Evaluation of Fire Spread and Suppression Techniques in Micro-Mobility Battery Packs

ECS Advances
Lithium-ion battery packs used in micro-mobility devices, such as e-bikes and e-scooters can lead to substantial safety hazards should a single cell go into thermal runaway.
Daniel A. Torelli, Nicholas Faenza, Phil Johns, Sam Lawton, James Frake   +4 more
doaj   +1 more source

The minimum exponent of the primitive digraphs on the given number of arcs [PDF]

Opuscula Mathematica, 2004
Primitive digraphs on \(n\) vertices, \(k\) arcs and girth \(s\) are considered. By \(a(n,k,s)\) we mean the minimum exponent taken over all such digraphs. We estimate the number \(a(n,k,s)\) using the Frobenius number for special values of \(k\) and \(s\
Jolanta Rosiak
doaj  

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

Molecular Oncology, EarlyView.
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas, Konstantinos Voutetakis, Vivian Kosmidou, Spyridon Tsikalakis, Spyridon Roditis, Konstantinos Pateas, Ryangguk Kim, Kymberleigh Pagel, Stephan Wolf, Gregor Warsow, Antonia Dimitrakopoulou‐Strauss, Georgios N. Zografos, Alexander Pintzas, Johannes Betge, Olga Papadodima, Stefan Wiemann   +15 more
wiley   +1 more source

On monochromatic arm exponents for 2D critical percolation [PDF]

Annals of Probability 2011, Vol. 39, No. 4, 1286-1304, 2009
We investigate the so-called monochromatic arm exponents for critical percolation in two dimensions. These exponents, describing the probability of observing j disjoint macroscopic paths, are shown to exist and to form a different family from the (now well understood) polychromatic exponents. More specifically, our main result is that the monochromatic
arxiv   +1 more source

Enhancing patient engagement in cancer research: a focus on patient‐centric approaches to scientific discovery

Molecular Oncology, EarlyView.
Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda, Marina Reguero, Vanesa Abón, Marta Puyol   +3 more
wiley   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source