Results 241 to 250 of about 4,815,078 (315)

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

Advanced NanoBiomed Research, EarlyView.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia, Akshay Pandey, Raffaele Spanò, Bianca Martins Estevão, Roberto Palomba, Greta Avancini, Tamaghna Gupta, Ana Maria Lopez Estevez, Stuart B. Goodman, Nidhi Bhutani, Paolo Decuzzi   +10 more
wiley   +1 more source

Genomic and transcriptomic analysis reveals chitin metabolic pathways in the marine bacterium Microbulbifer harenosus CGMCC 1.13584^T. [PDF]

BMC Microbiol
Ren X, Song X, Zhang H, Wang G, Xie F, Muhetaerhan H, Ai L, Tian Y.   +7 more
europepmc   +1 more source

Color‐Pure Organic Luminophores: Characteristics, Definitions, Physical Basis and Fundamental Design Principles

Angewandte Chemie, EarlyView.
Color‐pure all‐organic emitters, i.e., with narrow spectral characteristics, are intensively studied for high‐definition organic LEDs and multi‐color bioimaging. In order to guide targeted materials design, this educative review discusses spectral characteristics, proper definitions and units, and the physical basis of spectral broadening, to distill ...
Johannes Gierschner, Sunwu Song, Siyang Feng, Liangxuan Wang, Miguel Ródenas, Begoña Milián‐Medina, Min Sang Kwon   +6 more
wiley   +2 more sources

The phage Φ13-encoded transcriptional regulator Ltr controls phage assembly in Staphylococcus aureus. [PDF]

Virol J
Dobritz R, Bäcker M, Rohmer C, Korn N, Bisanzio V, Wolz C.   +5 more
europepmc   +1 more source

Transcriptomic dynamics reveals sequential acquisition of complement resistance during prolonged starvation of Trypanosoma cruzi epimastigote [PDF]

Mem Inst Oswaldo Cruz
Pérez-Díaz L, Smircich P, Hernandez F, Ciganda M, Duhagon MA, Garat B.   +5 more
europepmc   +1 more source

Descent from a common ancestor restricts exploration of protein sequence space. [PDF]

Proc Natl Acad Sci U S A
Isakova LH, Streltsova E, Bochkareva OO, Vlasov PK, Kondrashov FA.   +4 more
europepmc   +1 more source

Simplified dosimetry using two-time-point kinetic modeling of ¹²⁴I-MIBG PET for ¹³¹I-MIBG therapy in neuroblastoma. [PDF]

Med Phys
Wang Y, Huh Y, Matthay KK, Vo KT, Pampaloni MH, DuBois SG, Seo Y.   +6 more
europepmc   +1 more source

New Modified Generalized Inverted Exponential Distribution and Its Applications. [PDF]

Entropy (Basel)
Al-Saiary ZA, Al-Jammaz HH.
europepmc   +1 more source

Unveiling solitary and twinning kink solitons in (2+1)-dimensional modified Zakharov-Kuznetsov equation arising in electronics. [PDF]

Sci Rep
Al-Sawalha MM, Noor S, Shah R, Yasmin H.
europepmc   +1 more source

Nonparametric Tests for Exponentiality Against IFRA Alternatives Based on Cumulative Extropy Measures. [PDF]

Entropy (Basel)
Alqefari AA.
europepmc   +1 more source