Results 31 to 40 of about 39,105 (170)

Nonuniform exponential stability for evolution families on the real line

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2015
The purpose of the present paper is to investigate the problem of nonuniform exponential stability of evolution families on the real line using the input-output technique known in the literature as the Perron method for the study of exponential stability.
Morariu Claudia Isabela, Preda Petre
doaj   +1 more source

Monitoring of Social Network and Change Detection by Applying Statistical Process: ERGM [PDF]

open access: yesJournal of Optimization in Industrial Engineering, 2020
The statistical modeling of social network data needs much effort  because of the complex dependence structure of the tie variables. In order to formulate such dependences, the statistical exponential families of distributions can provide a flexible ...
Farshid Rajabi   +2 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

On Weak Exponential Expansiveness of Evolution Families in Banach Spaces

open access: yesThe Scientific World Journal, 2013
The aim of this paper is to give several characterizations for the property of weak exponential expansiveness for evolution families in Banach spaces. Variants for weak exponential expansiveness of some well-known results in stability theory (Datko (1973)
Tian Yue, Xiao-qiu Song, Dong-qing Li
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Asymptotic optimality of sequential designs for estimation

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1995
This paper is concerned with the problem of allocating a fixed number of trials between K independent populations from the exponential family, in order to estimate a linear combination of the means with squared error loss.
Kamel Rekab
doaj   +1 more source

ON THE MODELING OF BIOMEDICAL DATA SETS WITH A NEW GENERALIZED EXPONENTIATED EXPONENTIAL DISTRIBUTION

open access: yesJournal of Biostatistics and Epidemiology, 2023
Many experts in the field of distribution theory have focused on extending probability distributions utilizing extended families of continuous distributions to improve the modeling adaptability of the conventional probability distributions.
Ibrahim Sule   +2 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Group Invariance of Information Geometry on q-Gaussian Distributions Induced by Beta-Divergence

open access: yesEntropy, 2013
We demonstrate that the q-exponential family particularly admits natural geometrical structures among deformed exponential families. The property is the invariance of structures with respect to a general linear group, which transitively acts on the space
Shinto Eguchi, Atsumi Ohara
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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