Results 41 to 50 of about 1,487,842 (265)

Exponential Relationship Between Maximal Apnea Duration and Exercise Intensity in Non-apnea Trained Individuals

Frontiers in Physiology, 2022
It is well known that the duration of apnea is longer in static than in dynamic conditions, but the impact of exercise intensity on the apnea duration needs to be investigated.
Alexandre Guimard, Alexandre Guimard, Fabrice Joulia, Fabrice Joulia, Fabrice Prieur, Fabrice Prieur, Gauthier Poszalczyk, Gauthier Poszalczyk, Kader Helme, Kader Helme, François J. Lhuissier, François J. Lhuissier   +11 more
doaj   +1 more source

Possible Divergences in Tsallis' Thermostatistics

, 2013
Trying to compute the nonextensive q-partition function for the Harmonic Oscillator in more than two dimensions, one encounters that it diverges, which poses a serious threat to the whole of Tsallis' thermostatistics.
Plastino, A., Rocca, M. C.
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Non-Extensive Quantum Statistics with Particle - Hole Symmetry

, 2014
Based on Tsallis entropy and the corresponding deformed exponential function, generalized distribution functions for bosons and fermions have been used since a while.
Biro, T. S., Shen, K. M., Zhang, B. W.
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

On a New Integral Inequality: Generalizations and Applications

Axioms, 2022
In this paper, we present some generalizations and improvements of a new integral inequality from the 29th IMC in 2022. Some applications of our new results are also provided.
Huaping Huang, Wei-Shih Du
doaj   +1 more source

Exponential dichotomies of evolution operators in Banach spaces

, 2014
This paper considers three dichotomy concepts (exponential dichotomy, uniform exponential dichotomy and strong exponential dichotomy) in the general context of non-invertible evolution operators in Banach spaces.
B Sasu, B Sasu, DD Bainov, J Zhang, L Barreira, L Barreira, L Barreira, L Barreira, L Hatvani, LH Popescu, M Megan, M Megan, M Megan, Mihail Megan, N Lupa, Nguyen Minh Van, Nicolae Lupa, NT Huy, O Perron, P Preda, P Preda, P Preda, R Datko, R Nagel, RJ Sacker, SN Chow, T Caraballo   +26 more
core   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source