Results 61 to 70 of about 12,126,899 (315)

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Possible Divergences in Tsallis' Thermostatistics

open access: yes, 2013
Trying to compute the nonextensive q-partition function for the Harmonic Oscillator in more than two dimensions, one encounters that it diverges, which poses a serious threat to the whole of Tsallis' thermostatistics.
Plastino, A., Rocca, M. C.
core   +1 more source

Stretched-exponential decay functions from a self-consistent model of dielectric relaxation [PDF]

open access: yes, 2007
There are many materials whose dielectric properties are described by a stretched exponential, the so-called Kohlrausch-Williams-Watts (KWW) relaxation function.
A.V. Milovanov   +43 more
core   +2 more sources

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Solutions of fractional nabla difference equations - existence and uniqueness [PDF]

open access: yesOpuscula Mathematica, 2016
In this article, we discuss existence, uniqueness and dependency of solutions of nonlinear fractional nabla difference equations in a Banach space equipped with a suitable norm, using the contractive mapping approach. As an application of the established
Jagan Mohan Jonnalagadda
doaj   +1 more source

Exploring the Potential of Zirconium-89 in Diagnostic Radiopharmaceutical Applications: An Analytical Investigation

open access: yesBiomedicines, 2023
This study highlights the use of 89Zr-oxalate in diagnostic applications with the help of WinAct and IDAC2.1 software. It presents the biodistribution of the drug in various organs and tissues, including bone, blood, muscle, liver, lung, spleen, kidneys,
Ahmed M. A. Mostafa   +5 more
doaj   +1 more source

Simple quasi-exponential slope generator [PDF]

open access: yes, 1969
Circuitry for digitally generating an exponentially decaying wave function permits discrete values to be sampled from the exponential waveform for comparison with a binary number of specified accuracy.
Anderson, T. O., Hurd, W. J.
core   +1 more source

Exponential dichotomies of evolution operators in Banach spaces

open access: yes, 2014
This paper considers three dichotomy concepts (exponential dichotomy, uniform exponential dichotomy and strong exponential dichotomy) in the general context of non-invertible evolution operators in Banach spaces.
B Sasu   +26 more
core   +1 more source

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

open access: yesFEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen   +2 more
wiley   +1 more source

A Novel Measure of Uncertainty in the Dempster-Shafer Theory

open access: yesIEEE Access, 2020
In the Dempster-Shafer theory, how to quantitatively evaluate the quality of information is an essential issue and also an open issue. Many of measures of uncertainty have been proposed in previous work, whereas some measures among them had been proved ...
Ke Wen   +3 more
doaj   +1 more source

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