Results 31 to 40 of about 46,138 (245)
IEEE Access, 2023 Power system load forecasting model plays an important role in all aspects of power system planning, operation and control. Therefore, accurate power load forecasting provides an important guarantee for the stable operation of the power grid system. This
Hongsheng Xu +3 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Fault location in power distribution systems considering a dynamic load model
Ingeniería e Investigación, 2015 In the electrical power systems, load is one of the most difficult elements to be represented by an adequate mathematical model due to its complex composition and dynamic and non-deterministic behavior.
Harold Andres Cifuentes Chaves +2 more
doaj +1 more source
Models of SIV rebound after treatment interruption that involve multiple reactivation events.
PLoS Computational Biology, 2020 In order to assess the efficacy of novel HIV-1 treatments leading to a functional cure, the time to viral rebound is frequently used as a surrogate endpoint. The longer the time to viral rebound, the more efficacious the therapy.
Christiaan H van Dorp +4 more
doaj +1 more source
IEEE Access, 2020 Fault diagnosis of rolling bearing has been the focus of research. Bearing signals are often accompanied by similar information, resulting in redundancy between data.
Mei Ying Qiao +3 more
doaj +1 more source
Topology optimization of multiphase material structures under design dependent pressure loads [PDF]
International Journal for Simulation and Multidisciplinary Design Optimization, 2009 In this paper, design-dependent pressure loads are addressed for topology optimization problems of multiphase material structures. The modeling of unidirectional load distribution with respect to the material density is studied and mathematical ...
Gao Tong, Zhang Wei-hong
doaj +1 more source
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Influence of Load Modeling on the Cost of Ensuring Stability Using TSCOPF
IEEE Access, 2023 Load modeling significantly impacts the time-domain response of power systems in transient stability studies but this effect is often underestimated in Transient Stability Constrained Optimal Power flow (TSCOPF) studies.
Francisco Arredondo +4 more
doaj +1 more source
Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region
FEBS Open Bio, EarlyView.Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson +2 more
wiley +1 more source